ArticleBMC musculoskeletal disorders2022
Knee varus alters three-dimensional ankle alignment in standing- a study with upright computed tomography.
Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Application of upright multidetector CT in orthopedics and the musculoskeletal system: insights into anatomy, alignment, and biomechanics.Japanese journal of radiology · 2026Review
- Machine learning prediction of ACL loading during the wide lunge: a multifactorial coupling analysis based on kinematic and electromyographic signals.Frontiers in bioengineering and biotechnology · 2026Article
- Equivalence assessment of weight bearing cone beam CT and multidetector CT through 3D Knee bone modelling.Scientific reports · 2025Article
- Knee osteotomies significantly influence coronal ankle alignment: A radiographic analysis.Journal of experimental orthopaedics · 2025Article
- The Impact of Pes Planus on Knee Function and Its Association with Medial Compartment Knee Osteoarthritis.Journal of orthopaedic case reports · 2024Article
- CT in osteoarthritis: its clinical role and recent advances.Skeletal radiology · 2023Review
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundFor knee osteoarthritis (OA) treatment, it is important to correct the lower limb alignment including the foot. However, in the upright position, lower limb alignment is generally assessed from the body surface or radiographs, and it is a challenge to capture the exact characteristics of three-dimensional lower limb alignment. The purpose of the study was to measure lower limb alignment in patients with knee OA using upright computed tomography (CT) and radiography, and to identify features of knee joint deformity.
methodsA total of 45 limbs in 25 patients with knee OA were enrolled. The subjects underwent both upright CT and radiography for the whole lower limb in the standing position. The joint angles were calculated on both images. The degree of knee OA was classified according to Kellgren-Lawrence (KL) grade by referring to radiography, which is mainly based on the degree of articular cartilage loss and severity of osteophytes, and the characteristics or correlation between knee and ankle joint in each group was investigated.
resultsIn KL-I, there was an association between varus of the knee joint and internal rotation of the talocrural joint (r = 0.76, P < 0.05). In KL-II, there was an association between varus of the knee joint and eversion of the subtalar joint (r = 0.63, P < 0.05) and talocrural joint (r = - 0.65, P < 0.05). In KL-III, there was an association between varus of the knee joint and internal rotation of the subtalar joint (r = - 0.62, P < 0.05), and in KL-IV, there was an association between varus of the knee joint and internal rotation of the subtalar joint (r = - 0.58, P < 0.05).
conclusionsThe lower limb alignment of patients with knee OA in the standing position was found that as knee OA worsened, it became apparent that compensatory knee joint alignment depended on the ankle joint rather than the subtalar joint. The results may help in the rehabilitation of patients with knee OA, since the ankle joint alignment has a significant impact on the knee joint during coarse movements involving load.
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