Evidence map›Paper›PMID 35379037›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2023

WEB vs coiling in ruptured aneurysms: A propensity score matched comparison of safety and efficacy.

Alberto Nania, Simon Gatt, Rohan Banerjee, Maaz Bj Syed, Jakov Tiefenbach, Nicholas Dobbs, Johannes Du Plessis, Peter Keston, Johnathan Downer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Alberto NaniaNHS Lothian, Department of Clinical Neuroscience, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, Edinburgh, UK.ORCID 0000-0001-6300-2896
Simon GattNHS Lothian, Department of Clinical Neuroscience, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, Edinburgh, UK.
Rohan BanerjeeNHS Lothian, Department of Clinical Neuroscience, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, Edinburgh, UK.
Maaz Bj SyedUniversity of Edinburgh, 9-16 Chambers Street, Edinburgh EH8 9AG, Edinburgh, UK.
Jakov TiefenbachUniversity of Edinburgh, 9-16 Chambers Street, Edinburgh EH8 9AG, Edinburgh, UK.
Nicholas DobbsNHS Lothian, Department of Clinical Neuroscience, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, Edinburgh, UK.
Johannes Du PlessisNHS Lothian, Department of Clinical Neuroscience, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, Edinburgh, UK.
Peter KestonNHS Lothian, Department of Clinical Neuroscience, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, Edinburgh, UK.
Johnathan DownerNHS Lothian, Department of Clinical Neuroscience, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, Edinburgh, UK.ORCID 0000-0002-8272-092X
NHS Lothian · GBUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aim to compare the safety and efficacy of WEB with coiling for acutely ruptured aneurysms.

methodsAll consecutive ruptured aneurysms with width suitable for WEB (2-10 mm) treated over 5 years (1/1/2015 to 31/12/2019) were included. We recorded WFNS, Fisher grade, patient demographics and aneurysm characteristics (size, location, D/W and aspect ratio, lobulation). Primary endpoints were mRS status at 3 months, aneurysm occlusion on latest available imaging follow-up, retreatment rate and procedural complications. We applied propensity score matching using aneurysm morphology (size, D/N ratio, ASPECT ratio and lobulation) to optimise matching for WEB versus coil comparison and minimise the effects of confounding.

resultA total of 493 patients were identified, 97 treated with the WEB device. 1:1 propensity score matching was used to establish a matched group of 97 patients treated with coiling. The WEB arm showed 3% procedural complication rate, with no haemorrhagic complications and use of adjunctive device in 4%. Satisfactory occlusion on follow-up (mean 14 months) was 79%, with 19% retreatment rate. The coil arm had 8% complication rate, with use of an adjunctive device in 52% of cases (balloon 44%, stent 8%). Satisfactory occlusion on follow-up (mean 22 months) was 90%, with 8% retreatment rate.

conclusionTreatment of ruptured wide-necked bifurcation aneurysms with WEB has a lower complication rate than coiling with high rate of satisfactory occlusion. However, there was a higher retreatment rate when compared with patients treated with coiling. An adjunct device (balloon or stent), was used in over 50% of aneurysms in the coiling group.

Indexed as

Aneurysm, RupturedEmbolization, TherapeuticEndovascular ProceduresIntracranial AneurysmCerebral AngiographyFollow-Up StudiesHumansPropensity ScoreRetrospective StudiesStentsTreatment Outcomeaneurysmneuro-interventionnew device

Identifiers

PMID35379037
PMCPMC10399506
OpenAlexW4225771044

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.