Evidence map›Paper›PMID 35378942›Full record

ArticleJournal of healthcare engineering2022

Updated Pharmacological Effects of Total Phenolic Acid on the Meningeal Microcirculation in Mice.

Hui Zhao, Jiaojiao Jia, Ming Bai, Mingsan Miao

RetractedAbstract readRetracted Publication
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Hui ZhaoDepartment of Pharmacology, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Jiaojiao JiaCollege of Postgraduates, Henan University of Chinese Medicine, Zhengzhou 450000, China.
Ming BaiCollege of Postgraduates, Henan University of Chinese Medicine, Zhengzhou 450000, China.
Mingsan MiaoCollege of Postgraduates, Henan University of Chinese Medicine, Zhengzhou 450000, China.ORCID 0000-0002-7083-5885

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the effects of total phenolic acid on meningeal microcirculation in mice. Methods: A total of 84 healthy mice were randomly divided into the blank group, the model group, the positive control Western medicine group, the positive control Chinese medicine group, and the large, medium, and small doses of the total phenolic acid group, with 12 rats in each group. The corresponding drug was given to the group once a day for one week, and the litter was changed at 9 : 00 on the 6th day, and the water fasted. On the 7th day, the groups continued to be administered and weighed. After 1 h, the percentage of decrease in the perfusion of the mice was measured. Results: Compared with the blank group, the percentage of perfusion decreased significantly in the model group, indicating that the model was successful. Compared with the model group, the nimodipine group, the Naoluotong group, and the high-dose succulent total phenolic acid group were perfused. The percentage of decrease was significantly decreased ( Conclusion: Total phenolic acid can reduce the percentage of mean perfusion of microcirculation in animals and reduce brain damage.

Indexed as

HydroxybenzoatesAnimalsMiceMicrocirculationHydroxybenzoatesphenolic acid

Identifiers

PMID35378942
PMCPMC8976621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.