Evidence map›Paper›PMID 35378930›Full record

ArticlePeerJ2022

ExhauFS: exhaustive search-based feature selection for classification and survival regression.

Stepan Nersisyan, Victor Novosad, Alexei Galatenko, Andrey Sokolov, Grigoriy Bokov, Alexander Konovalov, Dmitry Alekseev, Alexander Tonevitsky

Abstract read
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stepan NersisyanFaculty of Biology and Biotechnology, HSE University, Moscow, Russia.
Victor NovosadFaculty of Biology and Biotechnology, HSE University, Moscow, Russia.
Alexei GalatenkoFaculty of Mechanics and Mathematics, Lomonosov Moscow State University, Moscow, Russia.
Andrey SokolovFaculty of Mechanics and Mathematics, Lomonosov Moscow State University, Moscow, Russia.
Grigoriy BokovFaculty of Mechanics and Mathematics, Lomonosov Moscow State University, Moscow, Russia.
Alexander KonovalovFaculty of Mechanics and Mathematics, Lomonosov Moscow State University, Moscow, Russia.
Dmitry AlekseevFaculty of Mechanics and Mathematics, Lomonosov Moscow State University, Moscow, Russia.
Alexander TonevitskyFaculty of Biology and Biotechnology, HSE University, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feature selection is one of the main techniques used to prevent overfitting in machine learning applications. The most straightforward approach for feature selection is an exhaustive search: one can go over all possible feature combinations and pick up the model with the highest accuracy. This method together with its optimizations were actively used in biomedical research, however, publicly available implementation is missing. We present ExhauFS-the user-friendly command-line implementation of the exhaustive search approach for classification and survival regression. Aside from tool description, we included three application examples in the manuscript to comprehensively review the implemented functionality. First, we executed ExhauFS on a toy cervical cancer dataset to illustrate basic concepts. Then, multi-cohort microarray breast cancer datasets were used to construct gene signatures for 5-year recurrence classification. The vast majority of signatures constructed by ExhauFS passed 0.65 threshold of sensitivity and specificity on all datasets, including the validation one. Moreover, a number of gene signatures demonstrated reliable performance on independent RNA-seq dataset without any coefficient re-tuning,

Indexed as

Breast NeoplasmsColorectal NeoplasmsFemaleHumansMachine LearningMicroarray AnalysisSoftwareClassificationExhauFSExhaustive searchFeature selectionSurvival regression

Identifiers

PMID35378930
PMCPMC8976470

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.