ArticleMaterials today. Bio2022
Granular honeycomb scaffolds composed of carbonate apatite for simultaneous intra- and inter-granular osteogenesis and angiogenesis.
Article in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 27 citations in OpenAlex.
- Strategic Uniaxial Macropore Sizing for Honeycomb-Structured Scaffolds for Enhanced Bone Reconstruction in Segmental Bone Defects.ACS omega · 2025Article
- Fabrication andRSC advances · 2025Article
- Carbonate Apatite Honeycomb Scaffold-Based Drug Delivery System for Repairing Osteoporotic Bone Defects.ACS applied materials & interfaces · 2024Article
- In vivo trial of bioresorbable mesh cages contained bone graft granules in rabbit femoral bone defects.Scientific reports · 2024Article
- Lamellar Septa-like Structured Carbonate Apatite Scaffolds with Layer-by-Layer Fracture Behavior for Bone Regeneration.Biomimetics (Basel, Switzerland) · 2024Article
- Reconstruction of Load-Bearing Segmental Bone Defects Using Carbonate Apatite Honeycomb Blocks.ACS materials Au · 2023Article
- Gear-shaped carbonate apatite granules with a hexagonal macropore for rapid bone regeneration.Computational and structural biotechnology journal · 2023Article
- 3D bioprinting of in situ vascularized tissue engineered bone for repairing large segmental bone defects.Materials today. Bio · 2022Article
- Channel Aperture Characteristics of Carbonate Apatite Honeycomb Scaffolds Affect Ingrowths of Bone and Fibrous Tissues in Vertical Bone Augmentation.Bioengineering (Basel, Switzerland) · 2022Article
- Effects of Scaffold Shape on Bone Regeneration: Tiny Shape Differences Affect the Entire System.ACS nano · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Granular porous calcium phosphate scaffolds are used for bone regeneration in dentistry. However, in conventional granules, the macropore interconnectivity is poor and has varying size. Herein, we developed a productive method for fabricating carbonate apatite honeycomb granules with uniformly sized macropores based on extrusion molding. Each honeycomb granule possesses three hexagonal macropores of ∼290 μm along its diagonal. Owing to these macropores, honeycomb granules simultaneously formed new and mature bone and blood vessels in both the interior and exterior of the granules at 4 weeks after implantation. The honeycomb granules are useful for achieving rapid osteogenesis and angiogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.