Evidence map›Paper›PMID 35378689›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2022

Trichosporon asahii causing subcutaneous mycoses in an immunocompetent patient: case report and a minireview.

Wdson Luis Lima Kruschewsky, Pedro Massaroni-Peçanha, Simone Bravim Maifrede, Marcelo Santos Leite, Tâmea Aparecida Linhares Pôssa, Felipe Alberto-Lei, Rodrigo Cayô, Paulo Mendes Peçanha, Sarah Santos Gonçalves

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Wdson Luis Lima KruschewskyHospital Universitário Cassiano Antônio de Moraes (HUCAM), Federal University of Espírito Santo (UFES), Vitoria, ES, Brazil.
Pedro Massaroni-PeçanhaHospital Infantil Nossa Senhora da Glória (HEINSG), Vitória, ES, Brazil.
Simone Bravim MaifredeCenter for Research in Medical Mycology, Department of Pathology, Federal University of Espírito Santo (UFES), Av. Marechal Campos, 1468, Vitoria, ES, 29040-090, Brazil.
Marcelo Santos LeiteUniversidade de Alfenas (UNIFENAS), Belo Horizonte, MG, Brazil.
Tâmea Aparecida Linhares PôssaUniversity of Vila Velha (UVV), Hospital de Vila Velha, Vila Velha, ES, Brazil.
Felipe Alberto-LeiLaboratório Alerta, Division of Infectious Diseases, Department of Internal Medicine, Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM), São Paulo, SP, Brazil.
Rodrigo CayôLaboratório Alerta, Division of Infectious Diseases, Department of Internal Medicine, Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM), São Paulo, SP, Brazil.
Paulo Mendes PeçanhaSection of Infectious Diseases, Department of Medicine, Hospital Universitário Cassiano Antônio de Moraes (HUCAM), Federal University of Espírito Santo (UFES), Vitoria, ES, Brazil.
Sarah Santos GonçalvesCenter for Research in Medical Mycology, Department of Pathology, Federal University of Espírito Santo (UFES), Av. Marechal Campos, 1468, Vitoria, ES, 29040-090, Brazil. sarah.tavares@ufes.br.ORCID http://orcid.org/0000-0003-4170-4445
Universidade Federal do Espírito Santo · BRUniversidade Federal de São Paulo · BRHospital Nossa Senhora da Conceição · BRUniversidade Vila Velha · BR

Funding

Fundação Estadual de Amparo à Pesquisa do Estado do Espírito Santo 111/2017
6 · The paper itself

Abstract

Trichosporon spp. are a constituent of the normal flora of humans that can cause both superficial and invasive infections, mainly in immunocompromised and immunocompetent hosts, respectively. Herein, we a report of Trichosporon asahii causing subcutaneous fungal infection (SFI) in an immunocompetent patient after carpal tunnel surgery. Although susceptible to fluconazole, the treatment of SFI failed even using high doses of this azole. The skin lesion improved following the administration of voriconazole. We conducted a literature minireview searching reports on SFI in immunocompetent patients to check for epidemiological, diagnostic, therapeutic, and outcome characteristics. A total of 32 cases were reported. Despite being uncommon, the clinical suspicion and early diagnosis of SFI in immunocompetent patients undergoing previous surgery are important. Our study indicated that the azoles are the most active antifungal agents against Trichosporon spp., except for fluconazole, and voriconazole can be considered the first therapeutic option.

Indexed as

DermatomycosesTrichosporonTrichosporonosisAntifungal AgentsAzolesBasidiomycotaFluconazoleHumansVoriconazoleAntifungal AgentsAzolesFluconazoleVoriconazoleFungal infectionSubcutaneous mycosesTrichosporonTrichosporonosis

Identifiers

PMID35378689
PMCPMC9433615
OpenAlexW4226286120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.