ArticleNeurospine2022
Hemostats in Spine Surgery: Literature Review and Expert Panel Recommendations.
Article in Neurospine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Efficacy and safety of topical versus intravenous tranexamic acid in spinal surgery: a systematic review and meta-analysis.BMC surgery · 2025Pooled it
- Efficacy and safety of tranexamic acid in cervical spine surgery: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Validated intraoperative bleeding severity scale (VIBe) for hemostasis assessment in lumbar spinal fusion: a prospective, randomized controlled trial.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Trial
- Total and Hidden Blood Loss in Biportal Endoscopic Versus Tubular-Based Minimally Invasive Transforaminal Lumbar Interbody Fusion.Clinics in orthopedic surgery · 2026Article
- Anatomy and Surgical Implications of the Lumbar Epidural Venous Plexus: A Risk Zone Framework.Cureus · 2026Review
- Efficacy of Preoperative Oral Clonidine in Spine Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of clinical medicine · 2026Review
- Surgical Treatment of Tethered Cord Syndrome by Release of Filum Terminalis: A Review.Children (Basel, Switzerland) · 2026Review
- A Comprehensive Review of SURGICEL®: Efficacy, Applications, and Radiological Insights in Surgery.Cureus · 2026Review
- Safety and efficacy of flowable microfibrillar collagen hemostat in an ovine model of lumbar laminectomy and open durotomy compared with the gelatin-thrombin hemostatic matrix and control.Frontiers in surgery · 2026Article
- Tranexamic acid in spinal surgery: a stratified protocol from the surgeon's point of view.Brain & spine · 2026Article
- BLEED-LESS: a scoping review on blood loss elimination in endoscopic decompression-lessons and literature on endoscopic spine surgery.Journal of spine surgery (Hong Kong) · 2025Review
- Antithrombotic therapy delays due to neurosurgical interventions after traumatic vertebral artery injuries increases stroke risk.Neurosurgical review · 2025Article
- Article
- An investigational time-course study using anAnnals of translational medicine · 2025Article
- Clinical Outcomes Following Treatment of Cervical Spondylotic Radiculopathy With Cervical Posterior Decompression Using Unilateral Biportal Endoscopic Technique: A Single Center Retrospective Series of 20 Patients.International journal of spine surgery · 2025Article
- Effective utilisation of rapid infusion catheters in perioperative care: a narrative review.BJA open · 2025Review
- Review
- Surgical options for ossification of the posterior longitudinal ligament of the cervical spine: a narrative review.Journal of orthopaedic surgery and research · 2024Review
- The Use of Bone Wax in Hemostatic Control for Total Knee and Hip Arthroplasties: A Systematic Review.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
Bleeding in spine surgery is a common occurrence but when bleeding is uncontrolled the consequences can be severe due to the potential for spinal cord compression and damage to the central nervous system. There are many factors that influence bleeding during spine surgery including patient factors and those related to the type of surgery and the surgical approach to bleeding. There are a range of methods that can be employed to both reduce the risk of bleeding and achieve hemostasis, one of which is the adjunct use of hemostatic agents. Hemostatic agents are available in a variety of forms and materials and with considerable variation in cost, but specific evidence to support their use in spine surgery is sparse. A literature review was conducted to identify the pre-, peri-, and postsurgical considerations around bleeding in spine surgery. The review generated a set of recommendations that were discussed and ratified by a wider expert group of spine surgeons. The results are intended to provide a practical guide to the selection of hemostats for specific bleeding situations that may be encountered in spine surgery.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.