Evidence map›Paper›PMID 35378471›Full record

ArticleDiagnostic microbiology and infectious disease2022

Comparison of SARS-CoV-2 molecular detection in nasopharyngeal swab, saliva, and gargle samples.

Gustavo Genelhoud, Douglas Adamoski, Regiane Nogueira Spalanzani, Lucas Bochnia-Bueno, Jaqueline Carvalho de Oliveira, Daniela Fiori Gradia, Ana Cláudia Bonatto, Roseli Wassem, Sonia Mara Raboni, Meri Bordignon Nogueira and 1 more

Abstract read
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Diagnostic performance, stability, and acceptability of self-collected saliva without additives for SARS-CoV-2 molecular diagnosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gustavo GenelhoudPost-graduation Program in Genetics, Department of Genetics, Universidade Federal do Paraná (UFPR), Curitiba, Brazil; Department of Genetics, Universidade Federal do Paraná, Curitiba, Brazil.
Douglas AdamoskiDepartment of Genetics, Universidade Federal do Paraná, Curitiba, Brazil; Present affiliation: Brazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil. Electronic address: douglas.adamoski@gmail.com.
Regiane Nogueira SpalanzaniLaboratory of Virology, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, Brazil.
Lucas Bochnia-BuenoLaboratory of Virology, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, Brazil.
Jaqueline Carvalho de OliveiraPost-graduation Program in Genetics, Department of Genetics, Universidade Federal do Paraná (UFPR), Curitiba, Brazil.
Daniela Fiori GradiaDepartment of Genetics, Universidade Federal do Paraná, Curitiba, Brazil.
Ana Cláudia BonattoDepartment of Genetics, Universidade Federal do Paraná, Curitiba, Brazil.
Roseli WassemDepartment of Genetics, Universidade Federal do Paraná, Curitiba, Brazil.
Sonia Mara RaboniLaboratory of Virology, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, Brazil.
Meri Bordignon NogueiraLaboratory of Virology, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, Brazil.
Patricia Savio de Araujo-SouzaDepartment of Genetics, Universidade Federal do Paraná, Curitiba, Brazil; Laboratory of Immunogenetics and Histocompatibility (LIGH), Department of Genetics, Universidade Federal do Paraná (UFPR), Curitiba, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nasopharyngeal swab is a gold standard for detecting SARS-CoV-2. However, the inconvenience of this method compelled us to compare its efficiency with saliva and gargle samples, which we collected sequentially from 229 individuals. Saliva outperformed gargle samples, constituting a reliable RNA viral source with similar performance to nasopharyngeal samples.

Indexed as

COVID-19SARS-CoV-2HumansMouthwashesNasopharynxRNA, ViralSalivaSpecimen HandlingMouthwashesRNA, ViralDetectionGargleRT-PCRSalivaSARS-CoV-2

Identifiers

PMID35378471
PMCPMC8908569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.