Evidence map›Paper›PMID 35378368›Full record

ArticleJournal of anxiety disorders2022

Distinguishing PTSD, complex PTSD, and borderline personality disorder using exploratory structural equation modeling in a trauma-exposed urban sample.

Abigail Powers, Jessica M Petri, Chelsea Sleep, Yara Mekawi, Emma C Lathan, Karen Shebuski, Bekh Bradley, Negar Fani

Open access · greenAbstract read
In one paragraph

Article in Journal of anxiety disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

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  13. Health-related quality of life in psychiatric outpatients: a cross-sectional study of associations with symptoms, diagnoses, and employment status.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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  20. Determinants of Care Pathways for C-PTSD Patients in French Psychotrauma Centers: A Qualitative Study.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Abigail PowersDepartment of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: Abigail.lott@emoryhealthcare.org.
Jessica M PetriDepartment of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Chelsea SleepCincinnati VA Medical Center, Cincinnati, OH, USA.
Yara MekawiDepartment of Psychological and Brain Sciences, University of Louisville, Louisville, KY, USA.
Emma C LathanDepartment of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Karen ShebuskiDepartment of Counseling and Psychological Services, Georgia State University, Atlanta, GA, USA.
Bekh BradleyDepartment of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA; Atlanta VA Medical Center, Atlanta, GA, USA.
Negar FaniDepartment of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · USCincinnati VA Medical Center · USGeorgia State University · USUniversity of Louisville · US

Funding

Genetic and Trauma-Related Risk Factors for PTSDR01MH071537 · NIMH · EMORY UNIVERSITY · PI RESSLER, KERRY J. · 2005 to 2014
$8.5M
Mechanisms of Intergenerational Impact of Maternal TraumaR01HD071982 · NICHD · EMORY UNIVERSITY · PI BRADLEY, BEKH · 2013 to 2017
$2.1M
Development, Trauma, and Genotype Effects on Biomarkers of Anxiety in ChildrenR01MH100122 · NIMH · EMORY UNIVERSITY · PI JOVANOVIC, TANJA · 2013 to 2017
$1.9M
Primary-Care Based Mindfulness Intervention for Chronically Traumatized IndividualsK23AT009713 · NCCIH · EMORY UNIVERSITY · PI LOTT, ABIGAIL POWERS · 2018 to 2021
$538k
Genetic and Trauma-Related Risk Factors for PTSD: From GWAS to FunctionR56MH071537 · NIMH · EMORY UNIVERSITY · PI RESSLER, KERRY J. · 2015 to 2015
$148k
The role of emotion dysregulation in PTSD symptomologyF32MH102890 · NIMH · EMORY UNIVERSITY · PI LOTT, ABIGAIL POWERS · 2014 to 2015
$102k
NCCIH NIH HHS K23 AT009713NICHD NIH HHS R01 HD071982NIMH NIH HHS F32 MH102890NIMH NIH HHS R01 MH071537NIMH NIH HHS R01 MH100122NIMH NIH HHS R56 MH071537
6 · The paper itself

Abstract

There is debate about the validity of the complex posttraumatic stress disorder (CPTSD) diagnosis and whether disturbances in self-organization (DSO) in CPTSD can be differentiated from borderline personality disorder (BPD). How PTSD is defined may matter. The present study used exploratory structural equation modeling (ESEM) to replicate and extend prior work by including two models to examine how PTSD (ICD-11, DSM-5), DSO, and BPD symptoms relate. Participants (N = 470; 98.1% women; 97.7% Black) were recruited from medical clinics within an urban hospital. PTSD, CPTSD, and BPD were assessed using semi-structured interviews and trauma-related avoidance, aggressive behavior, and anxious attachment were assessed using self-report measures. ESEM models of PTSD, DSO, and BPD symptoms were run. We found a three-factor ESEM model of CPTSD (ICD-11 PTSD and DSO symptoms) and BPD symptoms best fit the data and found support for discriminant validity between factors across trauma-related avoidance, aggressive behavior, and anxious attachment. For DSM-5 PTSD, a two-factor ESEM model was best-fitting (PTSD and DSO/BPD). The findings demonstrate clear distinguishing and overlapping features of ICD-11 PTSD, CPTSD, and BPD and the necessity to consider the diagnostic structure of PTSD in determining the additive value of CPTSD as a distinct construct.

Indexed as

Borderline Personality DisorderStress Disorders, Post-TraumaticDiagnostic and Statistical Manual of Mental DisordersFemaleHumansInternational Classification of DiseasesLatent Class AnalysisMaleBorderline personality disorderComplex posttraumatic stress disorderPosttraumatic stress disorderTrauma

Identifiers

PMID35378368
PMCPMC9107503
OpenAlexW4221064826

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.