Evidence map›Paper›PMID 35373870›Full record

ArticleJournal of internal medicine2022

Microbiological etiology in prosthetic valve endocarditis: A nationwide registry study.

Blerand Berisha, Sigurdur Ragnarsson, Lars Olaison, Magnus Rasmussen

Open access · hybridAbstract read
In one paragraph

Article in Journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
  2. Article
  3. Newly recognized typical microorganisms in intracardiac prosthetic material-related infective endocarditis: evidence behind their inclusion in the 2023 Duke-ISCVID criteria.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  4. Mitral valve abscess: echocardiographic imaging, microbiology, management, and outcomes.European heart journal. Imaging methods and practice · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Prosthetic valve infective endocarditis caused byEuropean heart journal. Case reports · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. The 2023 Duke-International Society for Cardiovascular Infectious Diseases Criteria for Infective Endocarditis: Updating the Modified Duke Criteria.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Blerand BerishaDivision of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Sigurdur RagnarssonDivision of Cardiothoracic Surgery, Department for Clinical Sciences Lund, Skane University Hospital and Lund University, Lund, Sweden.
Lars OlaisonDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Magnus RasmussenDivision of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.ORCID 0000-0003-1588-5473
Lund University · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProsthetic valve endocarditis (PVE) is a feared complication after heart valve surgery. Studies on differences in bacteriology in various types of PVE are limited.

objectivesThis study aimed to investigate the microbiology of PVE depending on the type of prosthetic valve and timing of diagnosis.

methodsA retrospective study based on the Swedish Registry on Infective Endocarditis focusing on PVE was conducted. The cohort was divided into mechanical and bioprosthetic valves; into endocarditis localization in the aortic, mitral, or tricuspid valve; and into early and late PVE. The microbiology in these groups was compared. Predictors of Staphylococcus aureus as the cause of PVE were examined by multivariable logistic regression.

resultsA total of 780 episodes of PVE in 749 patients were compared regarding the distribution of causative microbiological agents. The most common agents included alpha-hemolytic streptococci (29%), S. aureus (22%), enterococci (14%), coagulase-negative staphylococci (CoNS) (12%), and Cutibacterium acnes (6%). S. aureus was more commonly found on mechanical valves compared to bioprosthetic ones (36% vs. 17%, p < 0.001) whereas alpha-hemolytic streptococci, enterococci, and CoNS were more common on bioprosthetic valves. There were no significant differences in the microbiology of PVE affecting mitral or aortic valves or in cases of early and late PVE. Predictors for S. aureus as the cause of PVE were end-stage renal disease, intravenous drug use, mechanical valve, and tricuspid localization of endocarditis.

conclusionsThe type of prosthetic heart valve is associated with the causative pathogen. Patients with mechanical valves are more likely to have PVE caused by S. aureus.

Indexed as

EndocarditisEndocarditis, BacterialHeart Valve ProsthesisProsthesis-Related InfectionsHumansRegistriesRetrospective StudiesStaphylococcus aureusmicrobiological etiologyprosthetic valve endocarditisregistry studyStaphylococcus aureusvalve prosthesis

Identifiers

PMID35373870
PMCPMC9541636
OpenAlexW4223992467

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.