Evidence map›Paper›PMID 35373863›Full record

ArticleJournal of internal medicine2022

Impact of the post-COVID-19 condition on health care after the first disease wave in Lombardy.

Pier M Mannucci, Alessandro Nobili, Mauro Tettamanti, Barbara D'Avanzo, Alessia A Galbussera, Giuseppe Remuzzi, Ida Fortino, Olivia Leoni, Sergio Harari

Abstract read
In one paragraph

Article in Journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  5. Article
  6. Article
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  9. Article
  10. Article
  11. Article
  12. Article
  13. Post-COVID-19 Syndrome Clinical Pathway for the US Veterans Health Administration.Journal of clinical pathways : the foundation of value-based care · 2023
    Article
  14. Long Covid: where we stand and challenges ahead.Cell death and differentiation · 2022
    Review
  15. Article
  16. Article
  17. Impact of the COVID-19 Pandemic on Total and Cause-Specific Mortality in Pavia, Northern Italy.International journal of environmental research and public health · 2022
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pier M MannucciFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and University of Milan, Milan, Italy.
Alessandro NobiliDepartment of Health Policy, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.ORCID 0000-0002-7813-0572
Mauro TettamantiDepartment of Health Policy, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Barbara D'AvanzoDepartment of Health Policy, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Alessia A GalbusseraDepartment of Health Policy, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Giuseppe RemuzziDepartment of Health Policy, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Ida FortinoDirezione Generale Welfare, Regione Lombardia, Milan, Italy.
Olivia LeoniDirezione Generale Welfare, Regione Lombardia, Milan, Italy.
Sergio HarariDepartment of Clinical Sciences and Community Health, Università di Milano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLombardy was affected in the early months of 2020 by the SARS-CoV-2 pandemic with very high morbidity and mortality. The post-COVID-19 condition and related public health burden are scarcely known. SETTING AND

designUsing the regional population administrative database including all the 48,932 individuals who survived COVID-19 and became polymerase-chain-reaction negative for SARS-CoV-2 by 31 May 2020, incident mortality, rehospitalizations, attendances to hospital emergency room, and outpatient medical visits were evaluated over a mid-term period of 6 months in 20,521 individuals managed at home, 26,016 hospitalized in medical wards, and 1611 in intensive care units (ICUs). These data were also evaluated in the corresponding period of 2019, when the region was not yet affected by the pandemic. Other indicators and proxies of the health-care burden related to the post-COVID condition were also evaluated. MAIN

resultsIn individuals previously admitted to the ICU and medical wards, rehospitalizations, attendances to hospital emergency rooms, and out-patient medical visits were much more frequent in the 6-month period after SARS-CoV-2 negativization than in the same prepandemic period. Performances of spirometry increased more than 50-fold, chest CT scans 32-fold in ICU-admitted cases and 5.5-fold in non-ICU cases, and electrocardiography 5.6-fold in ICU cases and twofold in non-ICU cases. Use of drugs and biochemical tests increased in all cases.

conclusionsThese results provide a real-life picture of the post-COVID condition and of its effects on the increased consumption of health-care resources, considered proxies of comorbidities.

Indexed as

COVID-19SARS-CoV-2Delivery of Health CareHumansIntensive Care UnitsPandemicsadministrative databaseclinical sequalaeLombardy regionlong-COVIDpolypharmacypopulation studySARS-CoV-2

Identifiers

PMID35373863
PMCPMC9115275

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.