ReviewChemistryOpen2022
When Molecules Meet in Water-Recent Contributions of Supramolecular Chemistry to the Understanding of Molecular Recognition Processes in Water.
Review in ChemistryOpen, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 56 citations in OpenAlex.
- o-Terphenyl-Based Family of Conjugated Macrocycles: Selective Recognition of Phenylalanine in Water and Interaction With Insulin.Angewandte Chemie (International ed. in English) · 2026Article
- Use of Halogenated Units for the Construction of Artificial Carbohydrate Receptors.Molecules (Basel, Switzerland) · 2026Article
- Article
- A Synthetic Lectin for Glucuronate.ACS central science · 2025Article
- A Bambusuril Receptor Binds Charge Diffuse Anions in Water at Picomolar Concentrations.Angewandte Chemie (International ed. in English) · 2025Article
- Thermodynamics of Water Displacement from Binding Sites and its Contributions to Supramolecular and Biomolecular Affinity.Angewandte Chemie (International ed. in English) · 2025Article
- Supramolecular Materials and Strategies for Bioorthogonal Chemical Transformations.Chemical reviews · 2025Review
- Protein Recognition and Assembly by a Phosphocavitand.Journal of the American Chemical Society · 2025Article
- Problematic Attributions of Entropic and Hydrophobic Effects in Drug Interactions.ACS bio & med chem Au · 2025Review
- Molecular Tweezers for Biomimetic Recognition of Carbohydrates.Chembiochem : a European journal of chemical biology · 2025Review
- Rational Design of Supramolecular Receptors for Consistent Binding Affinities under High-Salinity Conditions.The Journal of organic chemistry · 2025Article
- Highly Rigid, Yet Conformationally Adaptable, BisporphyrinJournal of the American Chemical Society · 2025Article
- Synthetic molecular cage receptors for carbohydrate recognition.Nature reviews. Chemistry · 2025Review
- Selective aqueous anion recognition in an anionic host.iScience · 2024Article
- Distinction and Quantification of Noncovalent Dispersive and Hydrophobic Effects.Molecules (Basel, Switzerland) · 2024Review
- Recent Advancements in the Utilization ofMolecules (Basel, Switzerland) · 2024Review
- Chelating chloride using binuclear lanthanide complexes in water.Chemical science · 2023Article
- Cycloalkyl Groups as Building Blocks of Artificial Carbohydrate Receptors: Studies with Macrocycles Bearing Flexible Side-Arms.Molecules (Basel, Switzerland) · 2022Article
- When Molecules Meet in Water-Recent Contributions of Supramolecular Chemistry to the Understanding of Molecular Recognition Processes in Water.ChemistryOpen · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular recognition processes in water differ from those in organic solvents in that they are mediated to a much greater extent by solvent effects. The hydrophobic effect, for example, causes molecules that only weakly interact in organic solvents to stay together in water. Such water-mediated interactions can be very efficient as demonstrated by many of the synthetic receptors discussed in this review, some of which have substrate affinities matching or even surpassing those of natural binders. However, in spite of considerable success in designing such receptors, not all factors determining their binding properties in water are fully understood. Existing concepts still provide plausible explanations why the reorganization of water molecules often causes receptor-substrate interactions in water to be strongly exothermic rather than entropically favored as predicted by the classical view of the hydrophobic effect.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.