Evidence map›Paper›PMID 35373439›Full record

SynthesisANZ journal of surgery2022

Cardiac surgery on patients with COVID-19: a systematic review and meta-analysis.

Aashray K Gupta, Alasdair Leslie, Joseph N Hewitt, Joshua G Kovoor, Christopher D Ovenden, Suzanne Edwards, Justin C Y Chan, Michael G Worthington

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in ANZ journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. The Association of COVID-19 and Mortality in Hospitalizations With Coronary Artery Bypass Graft.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Cardiovascular surgery during the first wave of COVID-19 pandemic.Turk gogus kalp damar cerrahisi dergisi · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Aashray K GuptaDepartment of Surgery, University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-8038-0378
Alasdair LeslieUniversity of Adelaide, Discipline of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Joseph N HewittUniversity of Adelaide, Discipline of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID 0000-0003-2959-4554
Joshua G KovoorUniversity of Adelaide, Discipline of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID 0000-0002-3880-3840
Christopher D OvendenUniversity of Adelaide, Discipline of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID 0000-0001-8075-7852
Suzanne EdwardsAdelaide Health Technology Assessment, School of Public Health, University of Adelaide, Adelaide, South Australia, Australia.
Justin C Y ChanUniversity of Adelaide, Discipline of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Michael G WorthingtonDepartment of Cardiothoracic Surgery, Royal Adelaide Hospital, Adelaide, Australia.
Royal Adelaide Hospital · AUThe University of Adelaide · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe COVID-19 pandemic has had a significant impact on global surgery. In particular, deleterious effects of SARS-CoV-2 infection on the heart and cardiovascular system have been described. To inform surgical patients, we performed a systematic review and meta-analysis aiming to characterize outcomes of COVID-19 positive patients undergoing cardiac surgery.

methodsThe study protocol was registered with PROSPERO (CRD42021228533) and conformed with PRISMA 2020 and MOOSE guidelines. PubMed, Ovid MEDLINE and Web of Science were searched between 1 January 2019 to 24 February 2022 for studies reporting outcomes on COVID-19 positive patients undergoing cardiac surgery. Study screening, data extraction and risk of bias assessment were conducted in duplicate. Meta-analysis was conducted using a random-effects model where at least two studies had sufficient data for that variable.

resultsSearches identified 4223 articles of which 18 studies were included with a total 44 patients undergoing cardiac surgery. Within these studies, 12 (66.7%) reported populations undergoing coronary artery bypass graft (CABG) surgery, three (16.7%) aortic valve replacements (AVR) and three (16.7%) aortic dissection repairs. Overall mean postoperative length of ICU stay was 3.39 (95% confidence interval (CI): 0.38, 6.39) and mean postoperative length of hospital stay was 17.88 (95% CI: 14.57, 21.19).

conclusionThis systematic review and meta-analysis investigated studies of limited quality which characterized cardiac surgery in COVID-19 positive patients and demonstrates that these patients have poor outcomes. Further issues to be explored are effects of COVID-19 on decision-making in cardiac surgery, and effects of COVID-19 on the cardiovascular system at a cellular level.

Indexed as

Cardiac Surgical ProceduresCOVID-19HumansLength of StayPandemicsSARS-CoV-2aortic dissectionbypass graftingcardiac surgerycoronary arteryCOVID-19emergency surgery

Identifiers

PMID35373439
PMCPMC9111466
OpenAlexW4224067908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.