Evidence map›Paper›PMID 35373286›Full record

ReviewInteractive cardiovascular and thoracic surgery2022

Impella support as a bridge to heart surgery in patients with cardiogenic shock.

Shunsuke Saito, Ikuko Shibasaki, Taiki Matsuoka, Ken Niitsuma, Shotaro Hirota, Yasuyuki Kanno, Yuta Kanazawa, Masahiro Tezuka, Yusuke Takei, Go Tsuchiya and 3 more

Abstract readReview
In one paragraph

Review in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  15. Single center experience and early outcomes of Impella 5.5.Frontiers in cardiovascular medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shunsuke SaitoDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.ORCID 0000-0002-0829-2891
Ikuko ShibasakiDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Taiki MatsuokaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Ken NiitsumaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Shotaro HirotaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Yasuyuki KannoDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Yuta KanazawaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Masahiro TezukaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Yusuke TakeiDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Go TsuchiyaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Taisuke KonishiDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Koji OgataDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.
Hirotsugu FukudaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn patients with cardiogenic shock, delayed surgery after stabilization of haemodynamics and improvement in end-organ function by mechanical circulatory support is known to yield better outcomes than emergency surgery. We aimed to investigate the effectiveness of Impella (Abiomed, Danvers, MA, USA) as a bridge to cardiac surgery in patients with cardiogenic shock.

methodsWe reviewed 7 patients with cardiogenic shock who underwent Impella support as a bridge to cardiac surgery using cardiopulmonary bypass at our institution between April 2018 and August 2021.

resultsCardiogenic shock was caused by ventricular septal rupture in 3 patients, papillary muscle rupture in 1 and acute myocardial infarction in 3. Cardiac surgery was delayed by 1-7 (3.9 ± 2.5) days with Impella support after the diagnosis of cardiogenic shock, during which the hepatic and renal function of the patients improved significantly. Device-related or operation-related adverse events included re-exploration for bleeding in 3 patients, acute limb ischaemia due to thromboembolism in 1 and intraoperative aortic dissection in 1. Thirty-day mortality was 14.3%, and the cumulative survival was 71.4% at 1 year. The survival tended to be better than that in historical control group in which extracorporeal membrane oxygenation was used as a bridge to surgery (P = 0.0992).

conclusionsImpella is an effective tool for bridging patients with cardiogenic shock to surgery. This strategy may improve surgical outcomes in patients with cardiogenic shock. However, prolonged Impella support may increase significant adverse events, and further investigation is required to determine the optimal duration of support before surgery.

Indexed as

Cardiac Surgical ProceduresExtracorporeal Membrane OxygenationHeart-Assist DevicesHumansRetrospective StudiesShock, CardiogenicTreatment OutcomeBridge to surgeryCardiogenic shockDelayed surgeryEmergency surgeryImpella

Identifiers

PMID35373286
PMCPMC9297506

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.