Evidence map›Paper›PMID 35373219›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2019

Model-Based Recommendations for Optimal Surgical Placement of Epiretinal Implants.

Michael Beyeler, Geoffrey M Boynton, Ione Fine, Ariel Rokem

Open access · greenAbstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A Computational Model of Phosphene Appearance for Epiretinal Prostheses.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael BeyelerDepartment of Psychology, University of Washington, Seattle, WA 98195, USA.
Geoffrey M BoyntonDepartment of Psychology, University of Washington, Seattle, WA 98195, USA.
Ione FineDepartment of Psychology, University of Washington, Seattle, WA 98195, USA.
Ariel RokemInstitute for Neuroengineering (UWIN), University of Washington, Seattle, WA 98195, USA.
University of Washington · US

Funding

The Effects of Attention in Human Visual CortexR01EY012925 · NEI · UNIVERSITY OF WASHINGTON · PI BOYNTON, GEOFFREY M · 1999 to 2018
$5.6M
The Effects of Visual DeprivationR01EY014645 · NEI · UNIVERSITY OF WASHINGTON · PI FINE, IONE · 2004 to 2021
$5.3M
Learning to see again: biological constraints on cortical plasticity and the implications for sight restoration technologiesR01EY031312 · NEI · UNIVERSITY OF WASHINGTON · PI BOYNTON, GEOFFREY M, FINE, IONE · 2021 to 2025
$2.0M
Virtual prototyping for retinal prosthesis patientsK99EY029329 · NEI · UNIVERSITY OF WASHINGTON · PI BEYELER, MICHAEL · 2018 to 2019
$245k
NEI NIH HHS K99 EY029329NEI NIH HHS R01 EY012925NEI NIH HHS R01 EY014645NEI NIH HHS R01 EY031312
6 · The paper itself

Abstract

A major limitation of current electronic retinal implants is that in addition to stimulating the intended retinal ganglion cells, they also stimulate passing axon fibers, producing perceptual 'streaks' that limit the quality of the generated visual experience. Recent evidence suggests a dependence between the shape of the elicited visual percept and the retinal location of the stimulating electrode. However, this knowledge has yet to be incorporated into the surgical placement of retinal implants. Here we systematically explored the space of possible implant configurations to make recommendations for optimal intraocular positioning of the electrode array. Using a psychophysically validated computational model, we demonstrate that better implant placement has the potential to reduce the spatial extent of axonal activation in existing implant users by up to ~55%. Importantly, the best implant location, as inferred from a population of simulated virtual patients, is both surgically feasible and is relatively stable across individuals. This study is a first step towards the use of computer simulations in patient-specific planning of retinal implant surgery.

Indexed as

Axonal stimulationComputational modelRetinal implant surgery

Identifiers

PMID35373219
PMCPMC8975247
OpenAlexW2980246299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.