Evidence map›Paper›PMID 35373190›Full record

ArticleFrontiers in tropical diseases2021

The Pandemic Experience in Southeast Asia: Interface Between SARS-CoV-2, Malaria, and Dengue.

Christina Yek, Vu Sinh Nam, Rithea Leang, Daniel M Parker, Seng Heng, Kimsan Souv, Siv Sovannaroth, Mayfong Mayxay, Sazaly AbuBakar, R Tedjo Sasmono and 7 more

Abstract read
In one paragraph

Article in Frontiers in tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Christina YekDepartment of Critical Care Medicine, National Institutes of Health Clinical Center, Bethesda, MD, United States.
Vu Sinh NamNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Rithea LeangMinistry of Health, Phnom Penh, Cambodia.
Daniel M ParkerDepartment of Population Health and Disease Prevention, University of California, Irvine, Irvine, CA, United States.
Seng HengMinistry of Health, Phnom Penh, Cambodia.
Kimsan SouvMinistry of Health, Phnom Penh, Cambodia.
Siv SovannarothMinistry of Health, Phnom Penh, Cambodia.
Mayfong MayxayLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane, Laos.
Sazaly AbuBakarWHO Collaborating Center for Arbovirus Reference and Research (Dengue) and Tropical Infectious Diseases Research and Education Center, Universiti Malaya, Kuala Lumpur, Malaysia.
R Tedjo SasmonoEijkman Institute for Molecular Biology, Jakarta, Indonesia.
Nhu Duong TranNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Hang Khanh Le NguyenNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Chanthap LonInternational Center of Excellence in Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Phnom Penh, Cambodia.
Kobporn BoonnakDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Rekol HuyMinistry of Health, Phnom Penh, Cambodia.
Ly SovannMinistry of Health, Phnom Penh, Cambodia.
Jessica E ManningLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States.

Funding

International Research in Cambodia: Tropical Medicine and Vector Research ZIAAI001066 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI YEK, CHRISTINA · 2009 to 2025
$10.8M
Intramural NIH HHS ZIA AI001066
6 · The paper itself

Abstract

Southeast Asia (SEA) emerged relatively unscathed from the first year of the global SARS-CoV-2 pandemic, but as of July 2021 the region is experiencing a surge in case numbers primarily driven by Alpha (B.1.1.7) and subsequently the more transmissible Delta (B.1.617.2) variants. While initial disease burden was mitigated by swift government responses, favorable cultural and societal factors, the more recent rise in cases suggests an under-appreciation of prior prevalence and over-appreciation of possible cross-protective immunity from exposure to endemic viruses, and highlights the effects of vaccine rollout at varying tempos and of variable efficacy. This burgeoning crisis is further complicated by co-existence of malaria and dengue in the region, with implications of serological cross-reactivity on interpretation of SARS-CoV-2 assays and competing resource demands impacting efforts to contain both endemic and pandemic disease.

Indexed as

COVID-19denguemalariaSARS-CoV-2Southeast Asia

Identifiers

PMID35373190
PMCPMC8975143

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.