Evidence map›Paper›PMID 35373130›Full record

ArticleKidney3602022

COVID-19 in Patients with Glomerular Disease: Follow-Up Results from the IRoc-GN International Registry.

Meryl Waldman, Maria Jose Soler, Clara García-Carro, Liz Lightstone, Tabitha Turner-Stokes, Megan Griffith, Joan Torras, Laura Martinez Valenzuela, Oriol Bestard, Colin Geddes and 32 more

Open access · diamondAbstract read
In one paragraph

Article in Kidney360, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Long COVID and the kidney.Nature reviews. Nephrology · 2025
    Review
  2. Observational
  3. Article
  4. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia · 2022
    Review
  5. Perspective on COVID-19 vaccination in patients with immune-mediated kidney diseases: consensus statements from the ERA-IWG and EUVAS.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022
    Article
  6. Viral Glomerulopathy.Glomerular diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 7 countries.

Meryl WaldmanKidney Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Maria Jose SolerServei Nefrologia, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Clara García-CarroServei Nefrologia, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Liz LightstoneCentre for Inflammatory Disease, Department of Immunology and Inflammation, Faculty of Medicine, Imperial College London, United Kingdom.ORCID 0000-0002-4603-4076
Tabitha Turner-StokesCentre for Inflammatory Disease, Department of Immunology and Inflammation, Faculty of Medicine, Imperial College London, United Kingdom.
Megan GriffithImperial College Healthcare NHS Trust Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Joan TorrasNephrology Department, Bellvitge University Hospital, Clinical Science Department, Barcelona University, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0002-1135-7588
Laura Martinez ValenzuelaNephrology Department, Bellvitge University Hospital, Clinical Science Department, Barcelona University, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.
Oriol BestardServei Nefrologia, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Colin GeddesGlasgow Renal and Transplant Unit, Queen Elizabeth University Hospital, Glasgow, United Kingdom.
Oliver FlossmannDepartment of Nephrology, Royal Berkshire Hospital, Reading, United Kingdom.ORCID 0000-0001-5976-3609
Kelly L BudgeDepartment of Medicine, Renal Division, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0002-9929-8518
Chiara CantarelliDipartimento di Medicina e Chirurgia, Università di Parma, UO Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Enrico FiaccadoriDipartimento di Medicina e Chirurgia, Università di Parma, UO Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Marco DelsanteDipartimento di Medicina e Chirurgia, Università di Parma, UO Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.ORCID 0000-0003-0715-6764
Enrique MoralesDepartamento de Nefrología, Hospital Universitario 12 de Octubre/Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.ORCID 0000-0002-5824-6973
Eduardo GutierrezDepartamento de Nefrología, Hospital Universitario 12 de Octubre/Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
Jose A Niño-CruzDepartamento de Nefrología y Metabolismo Mineral Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Armando J Martinez-RuedaDepartamento de Nefrología y Metabolismo Mineral Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0000-0001-5765-4521
Giorgia ComaiDepartment of Experimental Diagnostic and Specialty Medicine (DIMES), Nephrology, Dialysis and Renal Transplant Unit, IRCCS-Azienda Ospedaliero-Universitaria de Bologna, Alma Mater Studiorum University of Bologna, Italy, Bologna, Italy.
Claudia BiniDepartment of Experimental Diagnostic and Specialty Medicine (DIMES), Nephrology, Dialysis and Renal Transplant Unit, IRCCS-Azienda Ospedaliero-Universitaria de Bologna, Alma Mater Studiorum University of Bologna, Italy, Bologna, Italy.
Gaetano La MannaDepartment of Experimental Diagnostic and Specialty Medicine (DIMES), Nephrology, Dialysis and Renal Transplant Unit, IRCCS-Azienda Ospedaliero-Universitaria de Bologna, Alma Mater Studiorum University of Bologna, Italy, Bologna, Italy.
Maria F SlonHospital Universitario de Navarra, Pamplona, Spain.
Joaquin ManriqueHospital Universitario de Navarra, Pamplona, Spain.ORCID 0000-0002-7713-1629
Alejandro AvelloRed de Investigación Renal (REDINREN), Instituto de Salud Carlos III, Madrid, Spain.ORCID 0000-0002-9987-0588
Raul Fernandez-PradoRed de Investigación Renal (REDINREN), Instituto de Salud Carlos III, Madrid, Spain.ORCID 0000-0002-5201-1137
Alberto OrtizRed de Investigación Renal (REDINREN), Instituto de Salud Carlos III, Madrid, Spain.
Smaragdi MarinakiClinic of Nephrology and Renal Transplantation, NKUA, Medical School, Laiko General Hospital, Athens, Greece.
Carmen Rita Martin VarasServicio de Nefrología, Hospital General de Segovia, Segovia, Spain.
Cristina Rabasco RuizHospital Universitario Reina Sofía, Cordoba, Spain.
Milagros Sierra-CarpioHospital San Pedro, Logroño La Rioja, Spain.
Rebeca García-AgudoNephrology Department La Mancha-Centro Hospital, Alcázar de San Juan, Ciudad Real, Spain.ORCID 0000-0003-0649-2766
Gema Fernández JuárezNephrology Department, Hospital Universitario Fundación Alcorcón, Madrid, Spain.
Alexander J HamiltonRenal Unit, Royal Devon and Exeter NHS Foundation Trust, United Kingdom.ORCID 0000-0002-0730-4897
Annette BruchfeldDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Constantina ChrysochouFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID 0000-0003-1966-5558
Lilian HowardKidney Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Smeeta SinhaFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID 0000-0003-4117-4085
Tim LeachPortsmouth Hospitals NHS Trust, Portsmouth, United Kingdom.
Irene Agraz PamplonaServei Nefrologia, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Umberto MaggioreDipartimento di Medicina e Chirurgia, Università di Parma, UO Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.ORCID 0000-0002-7468-9600
Paolo CravediDepartment of Medicine, Renal Division, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0001-7837-0923
Ospedale di Parma · ITVall d'Hebron Institut de Recerca · ESImperial College Healthcare NHS Trust · GBInstituto de Salud Carlos III · ESUniversity of Bologna · ITBellvitge University Hospital · ESHospital Universitario 12 De Octubre · ESIcahn School of Medicine at Mount Sinai · USInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXNational Institutes of Health · USSalford Royal NHS Foundation Trust · GBHospital General De Segovia · ESHospital San Pedro · ESHospital Universitario Fundación Alcorcón · ESHospital Universitario Reina Sofía · ESLaiko General Hospital of Athens · GRLinköping University · SEPortsmouth Hospitals NHS Trust · GBQueen Elizabeth University Hospital · GBRoyal Berkshire Hospital · GB

Funding

Mechanisms of complement-mediated podocyte injury in FSGSR01DK119431 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CRAVEDI, PAOLO · 2019 to 2021
$763k
NIDDK NIH HHS R01 DK119431
6 · The paper itself

Abstract

Background: The acute and long-term effects of severe acute respiratory syndrome coronavirus 2 infection in individuals with GN are still unclear. To address this relevant issue, we created the International Registry of COVID-19 infection in GN. Methods: We collected serial information on kidney-related and -unrelated outcomes from 125 GN patients (63 hospitalized and 62 outpatients) and 83 non-GN hospitalized patients with coronavirus disease 2019 (COVID-19) and a median follow-up period of 6.4 (interquartile range 2.3-9.6) months after diagnosis. We used logistic regression for the analyses of clinical outcomes and linear mixed models for the longitudinal analyses of eGFR. All multiple regression models were adjusted for age, sex, ethnicity, and renin-angiotensin-aldosterone system inhibitor use. Results: After adjustment for pre-COVID-19 eGFR and other confounders, mortality and AKI did not differ between GN patients and controls (adjusted odds ratio for AKI=1.28; 95% confidence interval [CI], 0.46 to 3.60; Conclusions: Pre-COVID-19 eGFR is the main risk factor for AKI regardless of GN diagnosis. However, GN patients are at higher risk of impaired eGFR recovery after COVID-19-associated AKI. These patients (especially those with high baseline proteinuria or a diagnosis of focal segmental glomerulosclerosis or minimal change disease) should be closely monitored not only during the acute phases of COVID-19 but also after its resolution.

Indexed as

Acute Kidney InjuryCOVID-19Follow-Up StudiesHumansRegistriesSARS-CoV-2COVID-19follow-up studiesglomerular and tubulointerstitial diseasesglomerular diseasekidney glomerulusregistries

Identifiers

PMID35373130
PMCPMC8967646
OpenAlexW3215587518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.