Evidence map›Paper›PMID 35373125›Full record

Observational studyKidney3602022

A Propensity Score-Matched Observational Study of Remdesivir in Patients with COVID-19 and Severe Kidney Disease.

Rituvanthikaa Seethapathy, Sophia Zhao, Joshua D Long, Ian A Strohbehn, Meghan E Sise

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Kidney360, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Therapeutic advances in COVID-19.Nature reviews. Nephrology · 2023
    Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rituvanthikaa SeethapathyDepartment of Medicine, Division of Nephrology, Massachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0002-5316-4610
Sophia Zhao
Joshua D Long
Ian A Strohbehn
Massachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Remdesivir is not currently approved for patients with eGFR <30 ml/min per 1.73 m Methods: This study was a retrospective cohort study of patients with COVID-19 hospitalized between May 2020 and January 2021 with eGFR <30 ml/min per 1.73 m Results: The overall cohort included 34 hospitalized patients who initiated remdesivir within 72 hours of hospital admission with eGFR<30 ml/min per 1.73 m Conclusions: In this propensity score-matched study, remdesivir was well tolerated in patients with eGFR <30 ml/min per 1.73 m

Indexed as

COVID-19 Drug TreatmentRenal InsufficiencyAdenosine MonophosphateAgedAlanineAntiviral AgentsFemaleHumansKidneyPropensity ScoreRenal DialysisRetrospective StudiesSARS-CoV-2Adenosine MonophosphateAlanineAntiviral Agentsremdesiviracute kidney injuryantiviralchronic kidney diseaseCOVID-19dialysispropensity scoreremdesivirSARS-CoV-2

Identifiers

PMID35373125
PMCPMC8967642
OpenAlexW4200142551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.