Evidence map›Paper›PMID 35372991›Full record

ArticleKidney3602021

Glomerular Disease in Temporal Association with SARS-CoV-2 Vaccination: A Series of 29 Cases.

Tiffany N Caza, Clarissa A Cassol, Nidia Messias, Andrew Hannoudi, Randy S Haun, Patrick D Walker, Rebecca M May, Regan M Seipp, Elizabeth J Betchick, Hassan Amin and 24 more

Open access · diamondAbstract read
In one paragraph

Article in Kidney360, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Long COVID and the kidney.Nature reviews. Nephrology · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. An Update on Viral Infection-Associated Collapsing Glomerulopathy.Advances in kidney disease and health · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors at 15 institutions in 1 country.

Tiffany N CazaArkana Laboratories, Little Rock, Arkansas.ORCID 0000-0001-8988-8998
Clarissa A CassolArkana Laboratories, Little Rock, Arkansas.ORCID 0000-0001-7536-6806
Nidia MessiasArkana Laboratories, Little Rock, Arkansas.
Andrew HannoudiUniversity of Michigan, Ann Arbor, Michigan.
Randy S HaunArkana Laboratories, Little Rock, Arkansas.
Patrick D WalkerArkana Laboratories, Little Rock, Arkansas.
Rebecca M MayArkana Laboratories, Little Rock, Arkansas.
Regan M SeippDuPage Medical Group, Naperville, Illinois.ORCID 0000-0002-8463-8751
Elizabeth J BetchickMethodist LeBonheur Healthcare-Germantown, Germantown, Tennessee.
Hassan AminThe Kidney Group of Memphis, Memphis, Tennessee.
Mandolin S ZiadieMemorial Regional Hospital, Miramar, Florida.
Michael HaderlieIowa Kidney Institute, Bingham Memorial Hospital, Blackfoot, Idaho.
Joy Eduwu-OkwuwaPermian Nephrology Associates, Midland, Texas.
Irina VanceaSouthern Colorado Nephrology Associates, Pueblo, Colorado.
Melvin SeekOcala Kidney Group, Ocala, Florida.
Essam B ElashiFirelands Physicians Group, Sandusky, Ohio.
Ganesh ShenoyLee Kidney Center, Lehigh Acres, Florida.
Sayeed KhalillullahNorth Florida Nephrology Associates, Tallahassee, Florida.
Jesse A FlaxenburgPikes Peak Nephrology, Colorado Springs, Colorado.
John BrandtDivision of Nephrology, University of New Mexico, Albuquerque, New Mexico.
Matthew J DiamondNephrology Associates (Augusta), Augusta, Georgia.
Adam FromeKidney Specialists of North Houston, Shenandoah, Texas.
Eugene H KimKidney and Hypertension Specialists PLLC, Manassas, Virginia.
Gregory SchlessingerRocky Mountain Kidney Care, Lone Tree, Colorado.
Erlandas UlozasCarle Nephrology, Urbana, Illinois.
Janice L WeatherspoonSouthern Crescent Nephrology, Stockbridge, Georgia.
Ethan Thomas HoerschgenSpringfield Nephrology Associates, Springfield, Missouri.ORCID 0000-0002-1377-2005
Steven L FabianRocky Mountain Kidney Care, Aurora, Colorado.
Sung Yong BaeEast Tennessee Nephrology, Knoxville, Tennessee.
Bilal IqbalKidney Specialists of Southern Nevada, Las Vegas, Nevada.
Kanwalijit K ChouhanIowa Kidney Physicians P.C., Des Moines, Iowa.
Zeina KaramMercy Clinic Nephrology, Washington, Missouri.
James T HenryRenal Care Associates, Fort Smith, Arkansas.
Christopher P LarsenArkana Laboratories, Little Rock, Arkansas.
Arkana Laboratories · USKidney Associates · USColorado Kidney Care · USDuPage Medical Group · USFirelands Regional Medical Center · USMemorial Hospital · USMemorial Regional Hospital · USMercy Clinic Neurology · USMethodist Le Bonheur Healthcare · USSouthern Colorado Clinic · USSouthern Crescent Technical College · USSpringfield Clinic · USTidewater Kidney Specialists · USUniversity of Michigan · USUniversity of New Mexico · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Immune responses to vaccination are a known trigger for a new onset of glomerular disease or disease flare in susceptible individuals. Mass immunization against SARS-CoV-2 in the COVID-19 pandemic provides a unique opportunity to study vaccination-associated autoimmune kidney diseases. In the recent literature, there are several patient reports demonstrating a temporal association of SARS-CoV-2 immunization and kidney diseases. Methods: Here, we present a series of 29 cases of biopsy-proven glomerular disease in patients recently vaccinated against SARS-CoV-2 and identified patients who developed a new onset of IgA nephropathy, minimal change disease, membranous nephropathy, ANCA-associated GN, collapsing glomerulopathy, or diffuse lupus nephritis diagnosed on kidney biopsies postimmunization, as well as recurrent ANCA-associated GN. This included 28 cases of Results: The patients with collapsing glomerulopathy were of Black descent and had two Conclusions: Glomerular disease to vaccination is rare, although it should be monitored as a potential adverse event.

Indexed as

COVID-19Glomerulonephritis, IGAApolipoprotein L1COVID-19 VaccinesHumansPandemicsSARS-CoV-2VaccinationAPOL1 protein, humanApolipoprotein L1COVID-19 VaccinesANCAAPOL1collapsing glomerulopathyCOVID-19crescentic glomerulonephritisglomerular and tubulointerstitial diseasesIgA nephropathylupus nephritismembranous nephropathyminimal change diseaseSARS-CoV-2 vaccine

Identifiers

PMID35372991
PMCPMC8785835
OpenAlexW3200711389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.