Evidence map›Paper›PMID 35372739›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2022

Investigation of a Model-based Time-over-threshold Technique for Phoswich Crystal Discrimination.

Haithem Bouziri, Catherine M Pepin, Konin Koua, Maher Benhouria, Caroline Paulin, Jinsong Ouyang, Marc Normandin, Jean-François Pratte, Georges El Fakhri, Roger Lecomte and 1 more

Abstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haithem BouziriInterdisciplinary Institute for Technological Innovation (3IT) and with the Department of Electrical and Computer Engineering, Université de Sherbrooke, Sherbrooke, QC, Canada J1K 0A5.
Catherine M PepinSherbrooke Molecular Imaging Center, Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, QC, Canada J1H 5N4.
Konin KouaInterdisciplinary Institute for Technological Innovation (3IT) and with the Department of Electrical and Computer Engineering, Université de Sherbrooke, Sherbrooke, QC, Canada J1K 0A5.
Maher BenhouriaInterdisciplinary Institute for Technological Innovation (3IT) and with the Department of Electrical and Computer Engineering, Université de Sherbrooke, Sherbrooke, QC, Canada J1K 0A5.
Caroline PaulinInterdisciplinary Institute for Technological Innovation (3IT) and with the Department of Electrical and Computer Engineering, Université de Sherbrooke, Sherbrooke, QC, Canada J1K 0A5.
Jinsong OuyangGordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114 USA.
Marc NormandinGordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114 USA.
Jean-François PratteInterdisciplinary Institute for Technological Innovation (3IT) and with the Department of Electrical and Computer Engineering, Université de Sherbrooke, Sherbrooke, QC, Canada J1K 0A5.
Georges El FakhriGordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114 USA.
Roger LecomteSherbrooke Molecular Imaging Center, Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, QC, Canada J1H 5N4.
Réjean FontaineInterdisciplinary Institute for Technological Innovation (3IT) and with the Department of Electrical and Computer Engineering, Université de Sherbrooke, Sherbrooke, QC, Canada J1K 0A5.

Funding

Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Kira Grogg · 2017 to 2026
$14.8M
Ultra High Resolution Brain PET Scanner for in-vivo Autoradiography ImagingU01EB027003 · NIBIB · YALE UNIVERSITY · PI EL FAKHRI, GEORGES, FONTAINE, RÉJEAN · 2018 to 2022
$4.6M
NIBIB NIH HHS P41 EB022544NIBIB NIH HHS U01 EB027003
6 · The paper itself

Abstract

The best crystal identification (CI) algorithms proposed so far for phoswich detectors are based on adaptive filtering and pulse shape discrimination (PSD). However, these techniques require free running analog to digital converters, which is no longer possible with the ever increasing pixelization of new detectors. We propose to explore the dual-threshold time-over-threshold (ToT) technique, used to measure events energy and time of occurence, as a more robust solution for crystal identification with broad energy windows in phoswich detectors. In this study, phoswich assemblies made of various combinations of LGSO and LYSO scintillators with decay times in the range 30 to 65 ns were investigated for the LabPET II detection front-end. The electronic readout is based on a 4 × 8 APD array where pixels are individually coupled to charge sensitive preamplifiers followed by first order CR-RC shapers with 75 ns peaking time. Crystal identification data were sorted out based on the measurements of likeliness between acquired signals and a time domain model of the analog front-end. Results demonstrate that crystal identification can be successfully performed using a dual-threshold ToT scheme with a discrimination accuracy of 99.1% for LGSO (30 ns)/LGSO (45 ns), 98.1% for LGSO (65 ns)/LYSO (40 ns) and 92.1% for LYSO (32 ns)/LYSO (47 ns), for an energy window of [350-650] keV. Moreover, the method shows a discrimination accuracy >97% for the two first pairs and

Indexed as

Crystal identificationdepth of interactionfront-end electronicsLGSOLYSOphoswichpositron emission tomographyradial spatial resolutionsignal processingtime-over-threshold

Identifiers

PMID35372739
PMCPMC8974315

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.