Evidence map›Paper›PMID 35372702›Full record

ArticleJournal of clinical tuberculosis and other mycobacterial diseases2022

Hemophagocytic lymphohistiocytosis: An unusual presentation of disseminated tuberculosis: A case report and literature review.

Poornachandra, Abdi Bati Wotiye, Biniyam A Ayele

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

PoornachandraConsultant Gastroenterologist and Hepatologist, Department of Gastroenterology and Hepatology, Fortis Hospital Bannerghatta Road, Banglore, Karnataka, India.
Abdi Bati WotiyeAssistant Professor of Gastroenterology and Hepatology, Department of Internal Medicine, All Africa leprosy, Tuberculosis, Rehabilitation and Training Center-ALERT Center, Addis Ababa Ethiopia, PO Box: 5164, Ethiopia.
Biniyam A AyeleAssistant professor of Neurology, Department of Neurology, College of Health Sciences, Addis Ababa University, PoBox 6396 Addis Ababa, Ethiopia.
Addis Ababa University · ETAll Africa Leprosy Tuberculosis and Rehabilitation Training Centre · ETFortis Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life-threatening syndrome associated with cytokine storm. Here, we present a patient with acquired HLH associated with Case presentation: We report a 66-year-old hypertensive and diabetic male patient who presented with four days history of fever and abdominal pain. Denied history of cough and weight loss. Laboratory investigation showed: elevated ferritin, C-reactive protein, and triglyceride. Bone marrow examination showed > 50% hemophagocytosis (RBCs and platelets ingested by macrophages), positive acid-fast bacillus for Conclusion: The present case highlights on the importance of early diagnosis and treatment of acquired HLH associated with tuberculous infection to improve the clinical outcome of the patient.

Indexed as

CRP, C reactive proteinCT, Computed tomographyHemophagocytic lymphohistiocytosisHIV, Human immune deficiency virusHLH, Hemophagocytic lymphohistiocytosisHyperinflammatory syndromeTB, TuberculosisTuberculosis

Identifiers

PMID35372702
PMCPMC8971949
OpenAlexW4220991877

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.