Evidence map›Paper›PMID 35372313›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Intratarget Microdosing for Deep Phenotyping of Multiple Drug Effects in the Live Brain.

Jennifer Kim, Sebastian W Ahn, Kyle Deans, Devon Thompson, Benjamin Ferland, Prajan Divakar, Christine Dominas, Oliver Jonas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jennifer KimDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Sebastian W AhnDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Kyle DeansDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Devon ThompsonDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Benjamin FerlandDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Prajan DivakarNanostring Technologies, Inc., Seattle, WA, United States.
Christine DominasDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Oliver JonasDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Brigham and Women's Hospital · USHarvard University · USNanostring Technologies (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A main impediment to effective development of new therapeutics for central nervous system disorders, and for the

Indexed as

Alzheimer’s diseasedrug sensitivityhigh-throughput screenin vivomicrodevicepolymer formulation

Identifiers

PMID35372313
PMCPMC8973214
OpenAlexW4220846497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.