Evidence map›Paper›PMID 35372134›Full record

ArticleFrontiers in cellular and infection microbiology2022

Characterization of Altered Oropharyngeal Microbiota in Hospitalized Patients With Mild SARS-CoV-2 Infection.

Yong-Lin Shi, Mao-Zhang He, Mao-Zhen Han, Hong-Ya Gui, Peng Wang, Jun-Ling Yu, Ying-Lu Ge, Yong Sun, Sheng-Hai Huang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The Impact of Aging Oral Health on Long COVID-19.Journal of dental research · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yong-Lin ShiAnhui Provincial Centers for Disease Control and Prevention, Hefei, China.
Mao-Zhang HeDepartment of Microbiology, The Key Laboratory of Microbiology and Parasitology of Anhui Province, The Key Laboratory of Zoonoses of High Institutions in Anhui, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.
Mao-Zhen HanSchool of Life Sciences, Anhui Medical University, Hefei, China.
Hong-Ya GuiDepartment of Microbiology, The Key Laboratory of Microbiology and Parasitology of Anhui Province, The Key Laboratory of Zoonoses of High Institutions in Anhui, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.
Peng WangAnhui Provincial Centers for Disease Control and Prevention, Hefei, China.
Jun-Ling YuAnhui Provincial Centers for Disease Control and Prevention, Hefei, China.
Ying-Lu GeAnhui Provincial Centers for Disease Control and Prevention, Hefei, China.
Yong SunAnhui Provincial Centers for Disease Control and Prevention, Hefei, China.
Sheng-Hai HuangDepartment of Microbiology, The Key Laboratory of Microbiology and Parasitology of Anhui Province, The Key Laboratory of Zoonoses of High Institutions in Anhui, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.
Anhui Provincial Center for Disease Control and Prevention · CNAnhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) remains a serious emerging global health problem, and little is known about the role of oropharynx commensal microbes in infection susceptibility and severity. Here, we present the oropharyngeal microbiota characteristics identified by full-length 16S rRNA gene sequencing through the NANOPORE platform of oropharynx swab specimens from 10 mild COVID-19 patients and 10 healthy controls. Our results revealed a distinct oropharyngeal microbiota composition in mild COVID-19 patients, characterized by enrichment of opportunistic pathogens such as

Indexed as

COVID-19MicrobiotaHumansOropharynxRNA, Ribosomal, 16SSARS-CoV-2RNA, Ribosomal, 16Sfull-length 16S rRNAmicrobial analysisnanopore sequencingoral microbiotaoral swab specimensSARS-CoV-2 patients

Identifiers

PMID35372134
PMCPMC8965315
OpenAlexW4220840581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.