Evidence map›Paper›PMID 35372052›Full record

ArticleFrontiers in oncology2022

Chemical and Biological Evidence of the Efficacy of Shengxian Decoction for Treating Human Lung Adenocarcinoma.

Kejuan Li, Fengming You, Qin Zhang, Ruijiao Yuan, Qianghua Yuan, Xi Fu, Yifeng Ren, Qian Wang, Xiaohong Li, Zhenya Zhang and 2 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kejuan LiCollege of Life Science, Sichuan Normal University, Chengdu, China.
Fengming YouTraditional Chinese Medicine (TCM) Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Qin ZhangCollege of Life Science, Sichuan Normal University, Chengdu, China.
Ruijiao YuanCollege of Life Science, Sichuan Normal University, Chengdu, China.
Qianghua YuanOncology Department, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xi FuOncology Department, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yifeng RenOncology Department, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Qian WangOncology Department, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xiaohong LiOncology Department, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Zhenya ZhangGraduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan.
Mototada ShichiriBiomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Japan.
Yue YuBiomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shengxian Decoction (SXT) is a traditional Chinese medicine prescription comprising several anti-cancer medicinal herbs. However, the anti-cancer effect of SXT has rarely been reported. Herein, we explored the therapeutic potential of SXT for the treatment of lung adenocarcinoma (LUAD). High-performance liquid chromatography analysis of crude SXT extract revealed the abundance of mangiferin, an established anti-cancer compound. The serum pharmacological evaluation revealed that serum SXT suppressed A549 lung cancer cell proliferation

Indexed as

anti-tumor agentChinese medicinelung cancerShengxian Decoctiontoxicity

Identifiers

PMID35372052
PMCPMC8975620

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.