ArticleQuantitative imaging in medicine and surgery2022
Quantitative analysis of liver function: 3D variable-flip-angle versus Look-Locker T1 relaxometry in hepatocyte-specific contrast-enhanced liver MRI.
Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Water-T1, PDFF, and T2* mapping of the liver using chemical shift-encoded MOLLI.Abdominal radiology (New York) · 2026Article
- A steady-state MR fingerprinting sequence optimization framework applied to the fast 3D quantification of fat fraction and water T1 in the thigh muscles.Magnetic resonance in medicine · 2025Article
- Advancing Myocardial T1 Mapping: A Comparative Study of the Frequency-Independent MFA Sequence and Standard MOLLI.NMR in biomedicine · 2025Article
- Optimization of hepatobiliary phase imaging in gadoxetic acid-enhanced magnetic resonance imaging: a narrative review.Quantitative imaging in medicine and surgery · 2023Review
- Application of A U-Net for Map-like Segmentation and Classification of Discontinuous Fibrosis Distribution in Gd-EOB-DTPA-Enhanced Liver MRI.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Gd-EOB-DTPA, a liver specific contrast agent with T1- shortening effects, is routinely used in clinical magnetic resonance imaging (MRI) for detection and characterization of focal liver lesions. Gd-EOB-DTPA-enhanced T1 relaxometry has recently received increasing attention as a tool for the quantitative analyses of liver function. However, this T1 relaxometry technique is limited due to various artifacts caused by B1 inhomogeneities and motion artifacts. This study aims to compare two different T1 relaxometry techniques for evaluating liver function as determined using a Methods: Ninety-six patients underwent gadoxetic acid-enhanced MRI of the liver at 3T and a Results: T1 relaxometry measurements based on MR sequences, VFA, and LL show a constant change in line with impaired liver function progression. Simple regression models showed a log-linear correlation of Conclusions: Both T1 relaxometry sequences are suitable for the evaluation of liver function based on
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.