ArticleCureus2022
Unique Case Reports of Tooth Sensitivity After Consuming Tetrabenazine.
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tooth sensitivity (TS), a common discomfort manifests as hypersensitivity, sharp and rapid pain, or shock-like sensation in response to tactile, thermal, or chemical stimuli which others perceive as normal, affecting a significant percentage of the population. Tetrabenazine, a vesicular monoamine transport 2 receptor inhibitor acting on presynaptic neuronal endings, is commonly used in acute dystonia treatment. Two cases are reported here, where the patient, after consuming tetrabenazine (TBZ), was noted to have TS after a week of treatment. On stopping TBZ and substituting it with oral anticholinergic, the adverse symptom disappeared and did not recur again. No drugs are yet known to cause TS as an adverse drug reaction, and this is the first report of drug-induced TS cases.
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