Evidence map›Paper›PMID 35371696›Full record

ArticleCureus2022

A Novel Finding of Lichenoid Drug Reaction From Ibrutinib Therapy.

Merin Reji, Kinchit K Shah

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Merin RejiInternal Medicine, Wake Forest Baptist Medical Center, Winston Salem, USA.
Kinchit K ShahInternal Medicine, Wake Forest Baptist Medical Center, Winston-Salem, USA.
Atrium Health Wake Forest Baptist · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ibrutinib is Burton's tyrosine kinase inhibitor used in the treatment of chronic lymphocytic leukemia and other conditions. This drug has been generally thought to be well tolerated, although studies have identified a few distinct adverse effects, including gastrointestinal discomfort, nausea, diarrhea, and atrial fibrillation. Regarding cutaneous findings, ibrutinib has only been linked to two self-limiting forms of mild rashes generally. In this report, we discuss a lichenoid drug reaction to ibrutinib in a patient with chronic lymphocytic leukemia severe enough to result in drug discontinuation. This adverse effect has not been previously reported to our knowledge.

Indexed as

allergydrug reactionhematologyibrutiniblichenoid

Identifiers

PMID35371696
PMCPMC8941677
OpenAlexW4213221290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.