ReviewNeuro-oncology practice2022
Understanding the effect of categorization of a continuous predictor with application to neuro-oncology.
Review in Neuro-oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Article
- Stronger hearts, weaker leaps? The cardiac power paradox in elite soccer.European journal of applied physiology · 2026Article
- NT-proBNP With Postoperative Complications and 2-Year Mortality Among Hip Fracture Patients: An Observational Cohort Study.Orthopaedic surgery · 2026Observational
- Post-COVID fatigue disproportionately affects women: evidence from the DEFEAT Corona cohort.Frontiers in public health · 2026Article
- Association Between Haemoglobin Variant Phenotypes and Red Blood Cell Parameters Among Pregnant Women: A Hospital-Based Cross-Sectional Study in Ghana.BioMed research international · 2026Article
- Development and Validation of Prognostic Models for Treatment Response of Patients with B-Cell Lymphoma: Standard Statistical and Machine-Learning Approaches.Journal of clinical medicine · 2025Article
- Genome-Wide Association Study of Cognitive Function in Population-Based Cohorts in Japan: The Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study.Genes, brain, and behavior · 2025Article
- LexArabic: A receptive vocabulary size test to estimate Arabic proficiency.Behavior research methods · 2024Article
- Performance of the Models Predicting In-Hospital Mortality in Patients with ST-Segment Elevation Myocardial Infarction with Predictors in Categorical and Continuous Forms.Sovremennye tekhnologii v meditsine · 2024Article
- Association Between Change in Body Mass Index and Knee and Hip Replacements: A Survival Analysis of Seven to Ten Years Using Multicohort Data.Arthritis care & research · 2023Article
- Psychological therapies for depression and cardiovascular risk: evidence from national healthcare records in England.European heart journal · 2023Article
- Researchers in rheumatology should avoid categorization of continuous predictor variables.BMC medical research methodology · 2023Article
- Agricultural activities and risk of central nervous system tumors among French farm managers: Results from the TRACTOR project.International journal of cancer · 2022Article
- Predictors of outcome following a body image treatment based on acceptance and commitment therapy for patients with an eating disorder.Journal of eating disorders · 2022Article
- Categorizing continuous biomarkers: More cons than pros.Neuro-oncology practice · 2022Article
- Insights into the role of extracellular-to-total body water ratio on neurocognitive decrements over time in Asians with type 2 diabetes.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many neuro-oncology studies commonly assess the association between a prognostic factor (predictor) and disease or outcome, such as the association between age and glioma. Predictors can be continuous (eg, age) or categorical (eg, race/ethnicity). Effects of categorical predictors are frequently easier to visualize and interpret than effects of continuous variables. This makes it an attractive, and seemingly justifiable, option to subdivide the continuous predictors into categories (eg, age <50 years vs age ≥50 years). However, this approach results in loss of information (and power) compared to the continuous version. This review outlines the use cases for continuous and categorized predictors and provides tips and pitfalls for interpretation of these approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.