Evidence map›Paper›PMID 35371440›Full record

ArticleClinical kidney journal2022

Associations between depressive symptoms and disease progression in older patients with chronic kidney disease: results of the EQUAL study.

Boukje C Eveleens Maarse, Nicholas C Chesnaye, Robbert Schouten, Wieneke M Michels, Willem Jan W Bos, Maciej Szymczak, Magdalena Krajewska, Marie Evans, Olof Heimburger, Fergus J Caskey and 5 more

Abstract read
In one paragraph

Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  13. A cross-sectional study on assessing depression among hemodialysis patients.Journal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Boukje C Eveleens MaarseDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0003-1763-3122
Nicholas C ChesnayeERA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Robbert SchoutenDepartment of Nephrology, OLVG Hospital, Amsterdam, The Netherlands.
Wieneke M MichelsDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Willem Jan W BosDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Maciej SzymczakDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.
Magdalena KrajewskaDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.
Marie EvansDepartment of Clinical Sciences Intervention and Technology, Karolinska University Hospital Huddinge, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-8650-5795
Olof HeimburgerDepartment of Clinical Sciences Intervention and Technology, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Fergus J CaskeyRenal Unit, Southmead Hospital, Bristol, UK.
Christoph WannerDepartment of Medicine, Division of Nephrology, University Hospital of Würzburg, Würzburg, Germany.ORCID https://orcid.org/0000-0001-9507-5301
Kitty J JagerERA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Friedo W DekkerDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Yvette MeulemanDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-9891-2109
EQUAL Study Investigators

Funding

Stanford Medicine Center for Longevity and Healthy Aging Research Education CoreP30AG059307 · NIA · STANFORD UNIVERSITY · PI ZOU, JAMES · 2018 to 2025
$4.9M
NIA NIH HHS P30 AG059307
6 · The paper itself

Abstract

Background: Depressive symptoms are associated with adverse clinical outcomes in patients with end-stage kidney disease; however, few small studies have examined this association in patients with earlier phases of chronic kidney disease (CKD). We studied associations between baseline depressive symptoms and clinical outcomes in older patients with advanced CKD and examined whether these associations differed depending on sex. Methods: CKD patients (≥65 years; estimated glomerular filtration rate ≤20 mL/min/1.73 m Results: Overall kidney function decline in 1326 patients was -0.12 mL/min/1.73 m Conclusions: There was no significant association between depressive symptoms at baseline and decline in kidney function over time in older patients with advanced CKD. Depressive symptoms at baseline were associated with a higher mortality rate in men.

Indexed as

chronic kidney diseaseclinical outcomeclinical trialdepressive symptomsepidemiologyjoint modelnephrology careprospective cohort studysurvival analysis

Identifiers

PMID35371440
PMCPMC8967670

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.