Evidence map›Paper›PMID 35371424›Full record

ArticleDermatology reports2022

The influence of Mediterranean diet in acne pathogenesis and the correlation with insulin-like growth factor-1 serum levels: Implications and results.

Mariabeatrice Bertolani, Eleonora Rodighiero, Roberta Saleri, Giuseppe Pedrazzi, Simona Bertoli, Alessandro Leone, Claudio Feliciani, Torello Lotti, Francesca Satolli

Open access · goldAbstract read
In one paragraph

Article in Dermatology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Gut-skin axis: Emerging insights for gastroenterologists-a narrative review.World journal of gastrointestinal pathophysiology · 2025
    Review
  5. Article
  6. Obesity: A Modulator in Acne Management.Acta dermato-venereologica · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Mariabeatrice BertolaniSection of Dermatology, Department of Medicine and Surgery, University of Parma.
Eleonora RodighieroSection of Dermatology, Department of Medicine and Surgery, University of Parma.
Roberta SaleriDepartment of Veterinary Science, University of Parma.
Giuseppe PedrazziDepartment of Medicine and Surgery, Unit of Neuroscience and Interdepartmental Centre of Robust Statistics, University of Parma.
Simona BertoliInternational Center for the Assessment of Nutritional Status, Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan.
Alessandro LeoneInternational Center for the Assessment of Nutritional Status, Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan.
Claudio FelicianiSection of Dermatology, Department of Medicine and Surgery, University of Parma.
Torello LottiUniversity Unit of Dermatology and Regenerative Medicine, University of Rome G. Marconi, Italy.
Francesca SatolliSection of Dermatology, Department of Medicine and Surgery, University of Parma.
University of Parma · ITIRCCS Istituto Auxologico Italiano · ITNutrition Sciences (Belgium) · BESechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne is a chronic inflammatory disease of the pilosebaceous unit, and its etiology is complex and multifactorial. The role of the diet in its pathogenesis is still debated. The purpose of this study was to assess the association between MD and IGF-1 in acne patients and, as secondary objective, the role of systemic treatment on IGF-1 serum levels, in accordance with the patients' diet. This study included 35 patients aged 14-30 years affected by acne and treated in line with the EDF guidelines. Patients were divided into 2 groups based on a questionnaire score assessing the adherence to the Mediterranean diet: the Mediterranean Group (score ≥6) and the Western Group (score< 5). IGF-1 serum levels were measured in all patients before and after treatment and then compared to healthy population. IGF-1 levels were higher in patients than in controls and in the Western group than in the Mediterranean group. We speculate that the Mediterranean diet can have a protective role in the pathogenesis of acne by acting on the systemic route of IGF-1.

Indexed as

AcneIGF-1Insulin Like Growth Factor-1Mediterranean diet

Identifiers

PMID35371424
PMCPMC8969872
OpenAlexW4225591021

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.