Evidence map›Paper›PMID 35371276›Full record

ArticleComputational and mathematical methods in medicine2022

Mechanism of Antibacterial Enhancement and Drug Resistance Based on Smart Medical Imaging on Antibiotics.

Yanxia Xing, Xiaowen An, Boyang Wang, Guifang Chang, He Zhu, Yang Yu

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yanxia XingCollege of Food Science and Project Engineering, Shandong Agriculture and Engineering University, Jinan, 250100 Shandong, China.
Xiaowen AnCollege of Food Science and Project Engineering, Shandong Agriculture and Engineering University, Jinan, 250100 Shandong, China.
Boyang WangCollege of Food Science and Project Engineering, Shandong Agriculture and Engineering University, Jinan, 250100 Shandong, China.
Guifang ChangCollege of Food Science and Project Engineering, Shandong Agriculture and Engineering University, Jinan, 250100 Shandong, China.
He ZhuCollege of Food Science and Project Engineering, Shandong Agriculture and Engineering University, Jinan, 250100 Shandong, China.ORCID https://orcid.org/0000-0002-3736-4145
Yang YuCollege of Food Science and Project Engineering, Shandong Agriculture and Engineering University, Jinan, 250100 Shandong, China.ORCID https://orcid.org/0000-0003-3403-8317

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the development of antibacterial, synergistic, and drug resistance research, the requirements for the specificity of antibiotics are getting higher and higher. In the research based on the specificity of antibiotics, this article uses intelligent medical image processing methods to study the specificity of the antibacterial efficiency of nanocopper oxide and the inhibition of drug resistance. Copper oxide nanorods have the properties of surface effect, quantum size effect, volume effect, and macroscopic quantum tunneling effect. Compared with ordinary copper oxide, the nanoscale gives them special properties of electricity, optics, and catalysis. In this article, in the research based on the specificity of antibiotics, the specificity of antimicrobial efficiency and drug resistance inhibition of nanocopper oxide are studied by using smart medical information processing methods. Drug sensitivity paper tablet method is a drug sensitivity experiment to determine drug sensitivity to make accurate and effective use of drugs for treatment. Colony growth method is used to take the equivalent volume of fermentation liquid at different times to determine the content of bacteria. In this article, Staphylococcus aureus is cultivated by the drug-sensitive disk method and the colony growth method. Then, according to this type of antibiotic and bacterial group combination, Staphylococcus aureus is divided into a penicillin group, nanocopper oxide group, and cephalosporin group. 0.5 g of the corresponding antibiotic was added to each group. TMP (trimethoprim) acts as a synergist, and the ratio of TMP to antibiotic is 1 : 5. Finally, we compared the inhibitory concentration indexes of the above three groups and inferred the synergistic effect of antibiotics and the inhibitory effect of drug resistance through the specificity of the antibiotics that the antibacterial activity was further studied. The results showed that the antibacterial effect of TMP combined with nano-CuO was 38% higher than that of the penicillin group and 41% higher than that of the cephalosporin group. In addition, the combined effect of TMP and antibiotics is greater than the combined effect of TMP and antibiotics alone. From the observation of smart medical system processing, it is speculated that the reason may be that they provide each other with a suitable environment. Because of this combined effect between the TMP and the antibiotic, it can influence each other. From the results, the combined effect is 48% higher than the combined effect. Therefore, according to the results of medical imaging, the combination of antibiotics and antibacterial synergists can improve specificity and antibacterial rate.

Indexed as

Anti-Bacterial AgentsBacteriaDiagnostic ImagingDrug ResistanceHumansMicrobial Sensitivity TestsAnti-Bacterial Agents

Identifiers

PMID35371276
PMCPMC8967524
OpenAlexW4226118667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.