Evidence map›Paper›PMID 35371258›Full record

ArticleInternational journal of endocrinology2022

Sex Differences in the TyG Index and Cardiovascular Risk Factors in Metabolically Obese Normal Weight Phenotype.

Xiaoyang Xu, Akshaya Srikanth Bhagavathula, Yong Zhang, Paul M Ryan, Jamal Rahmani, Xiaoya Qi

Open access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Xiaoyang XuPhysical Examination Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Akshaya Srikanth BhagavathulaDepartment of Social and Clinical Pharmacy, Charles University, Hradec Kralove, Czech Republic.ORCID https://orcid.org/0000-0002-0581-7808
Yong ZhangPhysical Examination Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Paul M RyanSchool of Medicine, University College Cork, Cork, Ireland.
Jamal RahmaniCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Xiaoya QiPhysical Examination Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.ORCID https://orcid.org/0000-0002-0998-1883
Dalian Medical University · CNCharles University · CZShahid Beheshti University of Medical Sciences · IRUniversity College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The triglyceride glucose (TyG) index is a novel surrogate marker of insulin resistance and increases cardiovascular disease risk. We sought to explore sex differences in the relationship between TyG and cardiovascular (CV) risk factors in metabolically obese normal weight (MONW) phenotype. Method: We analyzed data of 1208 healthy men and nonpregnant women enrolled in a population-based longitudinal study from January 2017-June 2020. MONW phenotype was defined by normal body mass index (BMI: 18-<25 kg/m Results: Of 1208 subjects, 350 (29%) were MONW phenotype (mean age (years): male: 43.5 ± 12.4 and female: 43.1 ± 12.7) and 858 were metabolically healthy normal weight (MHNW; Conclusion: Our study revealed that the TyG index may represent a cost-effective and informative screening tool for the high-risk MONW phenotype.

Identifiers

PMID35371258
PMCPMC8970881
OpenAlexW4221077580

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.