Evidence map›Paper›PMID 35370973›Full record

ArticleFrontiers in endocrinology2022

Selective Depletion of Adult GFAP-Expressing Tanycytes Leads to Hypogonadotropic Hypogonadism in Males.

Lucile Butruille, Martine Batailler, Marie-Line Cateau, Ariane Sharif, Valérie Leysen, Vincent Prévot, Pascal Vaudin, Delphine Pillon, Martine Migaud

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. The role of tanycytes in the regulation of energy balance.Reviews in endocrine & metabolic disorders · 2026
    Review
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Lucile ButruilleCNRS, IFCE, INRAE, Université de Tours, PRC, Nouzilly, France.
Martine BataillerCNRS, IFCE, INRAE, Université de Tours, PRC, Nouzilly, France.
Marie-Line CateauCNRS, IFCE, INRAE, Université de Tours, PRC, Nouzilly, France.
Ariane SharifUniv. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neurosciences & Cognition, UMR-S1172, Lille, France.
Valérie LeysenUniv. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neurosciences & Cognition, UMR-S1172, Lille, France.
Vincent PrévotUniv. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neurosciences & Cognition, UMR-S1172, Lille, France.
Pascal VaudinCNRS, IFCE, INRAE, Université de Tours, PRC, Nouzilly, France.
Delphine PillonCNRS, IFCE, INRAE, Université de Tours, PRC, Nouzilly, France.
Martine MigaudCNRS, IFCE, INRAE, Université de Tours, PRC, Nouzilly, France.
Centre National de la Recherche Scientifique · FRCentre Hospitalier Universitaire de Lille · FRLille Neurosciences & CognitionUniversité de Lille · FRUniversité de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In adult mammals, neural stem cells are localized in three neurogenic regions, the subventricular zone of the lateral ventricle (SVZ), the subgranular zone of the dentate gyrus of the hippocampus (SGZ) and the hypothalamus. In the SVZ and the SGZ, neural stem/progenitor cells (NSPCs) express the glial fibrillary acidic protein (GFAP) and selective depletion of these NSPCs drastically decreases cell proliferation

Indexed as

Ependymoglial CellsGlial Fibrillary Acidic ProteinHypogonadismAnimalsMaleMammalsMiceNeurogenesisNeuronsGlial Fibrillary Acidic Proteinglial fibrillary astrocytic protein, mouseadult neural stem/progenitor cellsglial fibrillary acidic proteinGnRHhypothalamusreproductionsexual behaviortanycytes

Identifiers

PMID35370973
PMCPMC8966543
OpenAlexW4221071418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.