Evidence map›Paper›PMID 35370948›Full record

ArticleFrontiers in endocrinology2022

Case Report: Hypoglycemia Due to a Novel Activating Glucokinase Variant in an Adult - a Molecular Approach.

Anojian Koneshamoorthy, Dilan Seniveratne-Epa, Genevieve Calder, Matthew Sawyer, Thomas W H Kay, Stephen Farrell, Thomas Loudovaris, Lina Mariana, Davis McCarthy, Ruqian Lyu and 11 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Genetic Variations in Hyperinsulinemic Hypoglycemia: Active versus Inactive Mutations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Anojian KoneshamoorthyDepartment of Endocrinology and Diabetes, St. Vincent's Hospital, Melbourne, VIC, Australia.
Dilan Seniveratne-EpaDepartment of Endocrinology and Diabetes, St. Vincent's Hospital, Melbourne, VIC, Australia.
Genevieve CalderDepartment of Endocrinology and Diabetes, St. Vincent's Hospital, Melbourne, VIC, Australia.
Matthew SawyerDepartment of Endocrinology and Diabetes, St. Vincent's Hospital, Melbourne, VIC, Australia.
Thomas W H KayDepartment of Endocrinology and Diabetes, St. Vincent's Hospital, Melbourne, VIC, Australia.
Stephen FarrellDepartment of Surgery, St. Vincent's Hospital, Melbourne, VIC, Australia.
Thomas LoudovarisSt. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Lina MarianaSt. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Davis McCarthySt. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Ruqian LyuSt. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Xin LiuSt. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Peter ThornCharles Perkins Centre, School of Medical Sciences, University of Sydney, Sydney, NSW, Australia.
Jason TongCharles Perkins Centre, School of Medical Sciences, University of Sydney, Sydney, NSW, Australia.
Lit Kim ChinDepartment of Diabetes and Endocrinology, Royal Children's Hospital, Melbourne, VIC, Australia.
Margaret ZacharinDepartment of Diabetes and Endocrinology, Royal Children's Hospital, Melbourne, VIC, Australia.
Alison TrainerDepartment of Genomic Medicine, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Shelby TaylorDepartment of Genomic Medicine, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Richard J MacIsaacDepartment of Endocrinology and Diabetes, St. Vincent's Hospital, Melbourne, VIC, Australia.
Nirupa SachithanandanDepartment of Endocrinology and Diabetes, St. Vincent's Hospital, Melbourne, VIC, Australia.
Helen E ThomasSt. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Balasubramanian KrishnamurthyDepartment of Endocrinology and Diabetes, St. Vincent's Hospital, Melbourne, VIC, Australia.
St Vincent's Hospital · AUSt Vincents Institute of Medical Research · AURoyal Children's Hospital · AUThe Royal Melbourne Hospital · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of an obese 22-year-old man with activating

Indexed as

GlucokinaseHypoglycemiaAdultGlucoseHumansInsulinInsulin SecretionMaleGlucokinaseGlucoseInsulincongenital hyperinsulinismglucokinasehyperplastic isletshypoglycemiaMODY

Identifiers

PMID35370948
PMCPMC8969599
OpenAlexW4220950949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.