ReviewFrontiers in neurology2022
Autoimmune and Paraneoplastic Chorea: A Review of the Literature.
Review in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Paraneoplastic Syndromes in Gallbladder Cancer: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Oromotor Dyskinesia and Emotional Lability Masquerading as Anti-NMDA Receptor Encephalitis.Indian journal of pediatrics · 2026Article
- Rare Co-Occurrence: Paraneoplastic Striatal Encephalitis with a Metastatic Lesion in Small Cell Lung Cancer.Annals of Indian Academy of Neurology · 2026Article
- Tetrabenazine-Responsive Choreo-Ballism and Akathisia After Cardioversion and Coronary Angiography: A Case Report.Cureus · 2026Article
- Cancer-related movement disorders: A scoping review and diagnostic approach.Neuro-oncology practice · 2025Review
- Concomitant pathologies and their impact on Huntington's disease. A brief review of current evidence.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Lupus Disguised as Chorea: Uncommon Presentation of a Common Disease.Clinical case reports · 2025Article
- Choreoathetosis as a rare complication of paraneoplastic syndrome: a case report in small cell lung cancer with positive anti-Hu antibodies.Proceedings (Baylor University. Medical Center) · 2025Article
- The Spectrum of Movement Disorders Associated with Systemic Lupus Erythematosus.Current neurology and neuroscience reports · 2024Review
- COVID-19 Vaccine-Related Movement Disorders: A Systematic Review.Journal of movement disorders · 2024Article
- Paraneoplastic neurological syndromes of small cell lung cancer.Postepy psychiatrii neurologii · 2024Review
- A case of immunotherapy-responsive autoimmune hemichorea.Annals of clinical and translational neurology · 2024Article
- Acute Hemichorea in an Elderly Patient With Positive Anti-centromere Antibodies and Lung Tumor.Cureus · 2024Article
- Gait instability, ophthalmoplegia, and chorea with orofacial dyskinesia in a man with anti-Ri antibodies: a case report.Frontiers in neurology · 2024Article
- An overview on CV2/CRMP5 antibody-associated paraneoplastic neurological syndromes.Neural regeneration research · 2023Article
- Hemiballism and chorea with acute/subacute onset: a retrospective series.Acta neurologica Belgica · 2023Article
- Chorea: An unusual manifestation of endocrine diseases.Frontiers in endocrinology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autoimmune chorea syndromes represent a vast array of paraneoplastic, parainfectious and idiopathic disorders. It is increasingly apparent that familiarity with these disorders is critically important, as they may be treatable or may be part of a syndrome requiring further work-up and monitoring. These disorders are mediated by an aberrant immunologic attack with resultant neuronal dysfunction, manifesting as chorea. These conditions are typically accompanied by other neurologic or systemic manifestations. In this review we outline the clinical features, epidemiologic factors, and delineate the specific antibodies associated with each of these autoimmune mediated disorders. We highlight up to date information regarding this heterogeneous group of disorders, including a discussion of parainfectious Sydenham's chorea; paraneoplastic syndromes associated with CRMP-5 (collapsin response mediated protein-5/CV2) and ANNA-1 (antineuronal nuclear antibody / Hu) antibodies, in addition to neuronal antibody-associated disorders including anti-NMDAR, LGI1 (leucine-rich glioma inactivated-1) and CASPR2 (contactin associated protein-2). We discuss the more recently described entities of IgLON5, which has evidence of both immunologic and degenerative pathophysiology, in addition to PDE-10A antibody-associated chorea. We also outline chorea secondary to systemic diseases including Systemic Lupus Erythematosus (SLE) and Primary Antiphospholipid Syndrome (PAPS). We provide a framework for diagnosis and treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.