Evidence map›Paper›PMID 35370922›Full record

ArticleFrontiers in neurology2022

Association of Essential Tremor With Dementia and Affective Disorders: A Meta-Analysis.

Yajun Shang, Xinjie Chen, Mingda Ai, Xiaoran Gao, Shujuan Dai, Mingjie Zhao, Cen Yang, Liangfeng Wang, Junyan Zhang, Lianmei Zhong and 2 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yajun ShangDepartment of Neurosurgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Xinjie ChenYunnan Provincial Clinical Research Center for Neurological Diseases, Kunming, China.
Mingda AiYunnan Provincial Clinical Research Center for Neurological Diseases, Kunming, China.
Xiaoran GaoDepartment of Surgery, Shenzhen University, Shenzhen, China.
Shujuan DaiYunnan Provincial Clinical Research Center for Neurological Diseases, Kunming, China.
Mingjie ZhaoYunnan Provincial Clinical Research Center for Neurological Diseases, Kunming, China.
Cen YangDepartment of Surgery, Shenzhen University, Shenzhen, China.
Liangfeng WangDepartment of Anesthesiology, The First Clinical Medical College of Kunming Medical University, Kunming, China.
Junyan ZhangBothwin Clinical Study Consultant, Shanghai, China.
Lianmei ZhongYunnan Provincial Clinical Research Center for Neurological Diseases, Kunming, China.
Tianhao BaoDepartment of Geriatrics, Kunming Medical University Affiliated Mental Health Center, Kunming, China.
Xiaolei LiuYunnan Provincial Clinical Research Center for Neurological Diseases, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The dementia and affective disorders are common non-motor features in patients with essential tremor (ET). However, the relationship of ET with cognitive impairments and affective disorders remains controversial. This meta-analysis aimed to analyze the association of ET with dementia and affective disorders. Methods: Original studies published from January 1999 to October 2019 were systematically searched from the database of Medline (OvidSP), EMBASE (OvidSP), and the Cochrane Central Register of Controlled Trials. Pooled standard mean difference (SMD, random effect model), odds ratios (ORs), relative risk (RR), and 95% Results: Compared with the Non-ET group, patients with ET had significantly lower Mini-Mental State Examination (MMSE) score ( Conclusion: The non-motor symptoms should not be neglected among patients with ET. However, the causal relationship between ET and dementia, depression, and anxiety is unclear.

Indexed as

anxietydementiadepressionessential tremormovement disorders

Identifiers

PMID35370922
PMCPMC8967984

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.