ArticleFrontiers in neurology2022
Do Muscle Changes Contribute to the Neurological Disorder in Spastic Paresis?
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 20 citations in OpenAlex.
- The Role of Radial Shockwave Therapy in Reducing Spasticity and Improving Upper-Limb Function Following Stroke.Journal of clinical medicine · 2026Article
- Review
- Spastic co-contraction: A misdirected central command.Clinical neurophysiology practice · 2026Article
- When medical training amplifies therapeutic nihilism: a cross-national study of healthcare professional attitudes toward stroke recovery in Central Africa.Frontiers in medicine · 2026Article
- Nursing care challenges and overcoming strategies among stroke patients.Journal of education and health promotion · 2026Article
- Impact of a 2-Month Program of Eccentric Training on Plantar Flexor Structure and Function in Hemiparesis After Stroke.Archives of rehabilitation research and clinical translation · 2025Article
- A rare case report of neuro-brucellosis with concurrence of depression, visual impairment, bilateral sensorineural hearing loss, and paraplegia.PLoS neglected tropical diseases · 2025Article
- Reliability of the Five Step Assessment and Its Coefficients of Impairment in Spastic Paresis.Archives of rehabilitation research and clinical translation · 2025Article
- Article
- Constraint-induced movement therapy reduced shoulder pain and improved function in subacute and chronic stroke: a cohort study.Frontiers in neurology · 2025Article
- Differences in muscle quality, muscle strength, and functional motor performance between people after stroke and age- and sex-matched apparently healthy adults: a cross-sectional study.Frontiers in neurology · 2025Article
- Serious Game with Electromyography Feedback and Physical Therapy in Young Children with Unilateral Spastic Cerebral Palsy and Equinus Gait: A Prospective Open-Label Study.Sensors (Basel, Switzerland) · 2024Article
- Article
- Exceptional improvement in chronic stroke through Guided Self-rehabilitation Contract: a case report study.Frontiers in rehabilitation sciences · 2024Article
- Increasing the Passive Range of Joint Motion in Stroke Patients Using Botulinum Toxin: The Role of Pain Relief.Toxins · 2023Article
- Emerging theory of sensitization in post-stroke muscle spasticity.Frontiers in rehabilitation sciences · 2023Review
- Where is the zero of Tardieu for proximal trans-joint lower limb muscles? The relevance for the estimation of muscle shortening and weakness.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: At the onset of stroke-induced hemiparesis, muscle tissue is normal and motoneurones are not overactive. Muscle contracture and motoneuronal overactivity then develop. Motor command impairments are classically attributed to the neurological lesion, but the role played by muscle changes has not been investigated. Methods: Interaction between muscle and command disorders was explored using quantified clinical methodology-the Five Step Assessment. Six key muscles of each of the lower and upper limbs in adults with chronic poststroke hemiparesis were examined by a single investigator, measuring the angle of arrest with slow muscle stretch (X Results: A total of 80 persons with chronic hemiparesis with complete lower limb assessments [27 women, mean age 47 (SD 17), time since lesion 8.8 (7.2) years], and 32 with upper limb assessments [18 women, age 32 (15), time since lesion 6.4 (9.3) years] were identified. The composite coefficient of shortening was greater in the lower than in the upper limb (0.12 ± 0.04 vs. 0.08 ± 0.04; Conclusion: In chronic hemiparesis, muscle shortening affects the lower limb particularly, and, beyond a threshold of severity, may alter descending commands. The latter might occur through chronically increased intramuscular tension, and thereby increased muscle afferent firing and activity-dependent synaptic sensitization at the spinal level.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.