Evidence map›Paper›PMID 35370746›Full record

ArticleFrontiers in pharmacology2022

Dopamine Homeostasis Imbalance and Dopamine Receptors-Mediated AC/cAMP/PKA Pathway Activation are Involved in Aconitine-Induced Neurological Impairment in Zebrafish and SH-SY5Y Cells.

Jie Zhou, Cheng Peng, Qiuju Li, Xiaoyu Yan, Liang Yang, Mengting Li, Xiaoyu Cao, Xiaofang Xie, Dayi Chen, Chaolong Rao and 3 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Jie ZhouKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Cheng PengKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Qiuju LiKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xiaoyu YanKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Liang YangKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Mengting LiKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xiaoyu CaoKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xiaofang XieKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Dayi ChenKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chaolong RaoKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Sizhou HuangDevelopment and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medicine, Chengdu Medical College, Chengdu, China.
Fu PengWest China School of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Xiaoqi PanKey Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chengdu University of Traditional Chinese Medicine · CNChengdu Medical College · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aconitine is one of the main bioactive and toxic ingredients of

Indexed as

AC/cAMP/PKAaconitinedopamine homeostasisdopamine receptorneurological impairment

Identifiers

PMID35370746
PMCPMC8971779
OpenAlexW4220817685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.