Evidence map›Paper›PMID 35370688›Full record

ArticleFrontiers in pharmacology2022

A Pharmacoinformatics Analysis of Artemisinin Targets and

Rui Tian, Yufei Li, Xiaofeng Wang, Jiajun Li, Yingqian Li, Shaosheng Bei, Huashan Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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  8. Microvascular significance of TGF-β axis activation in COVID-19.Frontiers in cardiovascular medicine · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rui TianDepartment of Anoenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yufei LiDepartment of Anoenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xiaofeng WangDepartment of Anoenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jiajun LiDepartment of Anoenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yingqian LiDepartment of Anoenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Shaosheng BeiDepartment of Anoenterology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Huashan LiDepartment of Anoenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNGuang’anmen Hospital · CNXiyuan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC), as an intractably treated disease, seriously affects the quality of life of patients and has an increase in terms of incidence and prevalence annually. However, due to the lack of a direct etiology and drug-induced side effects, the medical treatment of UC falls into a bottleneck. There are many natural phytochemicals with the potential to regulate immune function in nature. Herein, a potential mechanism of artemisinin in the treatment of UC and potential druggability compounds with an artemisinin peroxide bond were discussed and predicted based on computer-aided drug design (CADD) technology by using the methods of network pharmacology, molecular docking,

Indexed as

artemisininMolAIcalmolecular dockingmolecular dynamicsulcerative colitis

Identifiers

PMID35370688
PMCPMC8971781
OpenAlexW4220789699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.