Evidence map›Paper›PMID 35370637›Full record

ArticleFrontiers in pharmacology2022

Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells

Linqian Peng, Yunwei Chen, Yan Li, Panpan Feng, Yan Zheng, Yongjie Dong, Yunjing Yang, Ruiyu Wang, Ailing Li, Jianghong Yan and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Superficial Parasternal Intercostal Plane Block and Full Sternotomy; A Randomized Trial.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Linqian PengDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yunwei ChenDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yan LiDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Panpan FengDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yan ZhengDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yongjie DongDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yunjing YangDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ruiyu WangDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ailing LiDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jianghong YanInstitute of Life Science, Chongqing Medical University, Chongqing, China.
Feifei ShangInstitute of Life Science, Chongqing Medical University, Chongqing, China.
Ping TangDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Dewei ChenInstitute of Medicine and Equipment for High Altitude Region, College of High Altitude Military Medicine, Army Medical University, Chongqing, China.
Yuqi GaoInstitute of Medicine and Equipment for High Altitude Region, College of High Altitude Military Medicine, Army Medical University, Chongqing, China.
Wei HuangDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CNArmy Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) is an incurable disease with high mortality. Chemerin has been found to be associated with pulmonary hypertension (PH). However, the specific role of chemerin in mediating PH development remains unclear. This study aimed to elucidate the regulatory effects and the underlying mechanism of chemerin on PH and to investigate the expression levels of chemerin protein in plasma in PAH patients.

Indexed as

chemerinchemokine-like receptor 1ERK1/2pulmonary arterial hypertensionpulmonary arterial smooth muscle cells

Identifiers

PMID35370637
PMCPMC8971604
OpenAlexW4220954982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.