Evidence map›Paper›PMID 35370554›Full record

ArticleFrontiers in cellular neuroscience2022

Sulforaphane Ameliorates Metabolic Changes Associated With Status Epilepticus in Immature Rats.

Jan Daněk, Šárka Danačíková, David Kala, Jan Svoboda, Sonam Kapoor, Antonín Pošusta, Jaroslava Folbergrová, Kateřina Tauchmannová, Tomáš Mráček, Jakub Otáhal

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jan DaněkInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Šárka DanačíkováInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
David KalaInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Jan SvobodaInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Sonam KapoorInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Antonín PošustaInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Jaroslava FolbergrováInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Kateřina TauchmannováInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Tomáš MráčekInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Jakub OtáhalInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Czech Academy of Sciences · CZCzech Academy of Sciences, Institute of Physiology · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Status epilepticus (SE) is a common paediatric emergency with the highest incidence in the neonatal period and is a well-known epileptogenic insult. As previously established in various experimental and human studies, SE induces long-term alterations to brain metabolism, alterations that directly contribute to the development of epilepsy. To influence these changes, organic isothiocyanate compound sulforaphane (SFN) has been used in the present study for its known effect of enhancing antioxidative, cytoprotective, and metabolic cellular properties

Indexed as

braincerebral blood flow (CBF)glucose metabolismimmature ratpilocarpinestatus epilepticussulforaphaneμCT/PET

Identifiers

PMID35370554
PMCPMC8965559
OpenAlexW4220871019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.