ReviewTobacco use insights2022
E-Cigarettes-a review of the evidence-harm versus harm reduction.
Review in Tobacco use insights, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Prevalence and determinants of e-cigarette use in South Asia: a systematic review.BMJ global health · 2025Pooled it
- Inflammatory and Carcinogenic Biomarker Signatures in E-Cigarette Users: A Comprehensive Meta-Analysis of ∼24,000 Adults.International journal of public health · 2025Pooled it
- Comparison of Acute Effects of E-cigarettes With and Without Nicotine and Tobacco Cigarettes on Hemodynamic and Endothelial Parameters: A Systematic Review and Meta-analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Pooled it
- Article
- Reduced vascular function, ventilatory efficiency and exercise capacity in young adult electronic cigarette users.ERJ open research · 2026Article
- Impact of E-Liquids on Phagocytosis, Escape and Invasion ofPathogens (Basel, Switzerland) · 2026Article
- Developing Tobacco Risk Communications for Young Adults Susceptible to Dual Use of Combustible Cigarettes and Nicotine Vapes: Mixed Methods Study.JMIR formative research · 2026Article
- Pain is Associated with E-Cigarette Use and Dependence in Young Adults: Findings from Wave 7 (2022-2023) of the Population Assessment of Tobacco and Health (PATH) Study.International journal of behavioral medicine · 2026Article
- Perceived risk of substance use and associations with early experimentation: A latent profile analysis using ABCD study data.Drug and alcohol dependence reports · 2026Article
- Emerging multisystem disease mechanisms of e-cigarette vaping on human health.Toxicology reports · 2026Review
- Evaluation of Acute Exposure to Combustible and Novel Tobacco Products Using an In Vitro Human Airway Organ Tissue Equivalent Model.Journal of applied toxicology : JAT · 2026Article
- Health warnings for electronic cigarette packaging: a rapid scoping review.BMC public health · 2026Article
- Article
- Effects of menthol cigarette and e-cigarette flavour restrictions on tobacco product purchasing: insights from the Experimental Tobacco Marketplace.Tobacco control · 2026Article
- A timeless chronicle: Effects of cigarette smoke on GPR15 receptor and its oncogenic potential.Cancer letters · 2026Review
- The effect of vaping on the human lung microbiota.Inhalation toxicology · 2026Article
- Awareness and use of e-cigarettes among Filipino adults: evidence from the 2015 and 2021 Global Adult Tobacco Surveys.BMJ public health · 2026Article
- E-cigarette use and associated factors among adolescents and young adults in northern Thailand: evidence from a population-based household survey.Frontiers in public health · 2026Article
- Prevalence and correlates of ever and current dual use of cigarettes and e-cigarettes among adolescents in Saudi Arabia.Internal and emergency medicine · 2026Article
- Understanding barriers and identifying solutions for smoking cessation in primary care: survey results informed by an integrated knowledge translation approach in British Columbia, Canada.BMJ open quality · 2025Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The World Health Organization estimates there are 1.1 billion cigarette smokers across the globe and that tobacco related deaths number 7 million per year. Electronic nicotine delivery systems (ENDS) are available to contribute options for smoking cessation and include e-cigarettes, e-hookahs, vape pens, mods, and vaping. The growing use of ENDS, or e-cigarettes, in the US and globally across populations is dramatic. Although users may think that e-cigarettes are less harmful than combustible tobacco products, the evidence shows that there are known risks and harms for users. E-cigarettes have varying amounts of toxicants, nicotine, and carcinogens and put the user at risk for lung diseases and COVID-19 similar to smokers. Currently, most governing bodies have not approved e-cigarettes as a smoking cessation tool but do state if a person has failed conventional smoking cessation treatments that e-cigarettes used alone for the short term may help those to quit combustible tobacco and nicotine. A shared decision-making approach should be used when discussing e-cigarettes as a harm reduction tool. More studies and long-term data are needed to assess potential benefits and harms. What is known is that prevention efforts and policy are needed to avoid adolescents and other vulnerable populations from initiating tobacco or e-cigarette use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.