Evidence map›Paper›PMID 35370415›Full record

ArticleJournal of inflammation research2022

Seminal Levels of Omentin-1/ITLN1 in Inflammatory Conditions Related to Male Infertility and Localization in Spermatozoa and Tissues of Male Reproductive System.

Elena Moretti, Cinzia Signorini, Daria Noto, Sergio Antonio Tripodi, Andrea Menchiari, Ester Sorrentino, Giulia Collodel

Open access · goldAbstract read
In one paragraph

Article in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Advances in immunological research on male infertility.Frontiers in reproductive health · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. The Molecular Basis of Male Infertility in Obesity: A Literature Review.International journal of molecular sciences · 2023
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Elena MorettiDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.ORCID 0000-0002-9467-0501
Cinzia SignoriniDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.ORCID 0000-0003-0006-9414
Daria NotoDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.ORCID 0000-0002-1571-9056
Sergio Antonio TripodiDepartment of Pathology Unit, AOUS Siena, Siena, Italy.ORCID 0000-0003-2019-4730
Andrea MenchiariDepartment of Business and Law, University of Siena, Siena, Italy.
Ester SorrentinoDepartment of Pathology Unit, AOUS Siena, Siena, Italy.ORCID 0000-0002-7875-8685
Giulia CollodelDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.ORCID 0000-0003-1587-0159
University of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Omentin-1/intelectin (ITLN)1 is an adipocytokine with both anti-inflammatory and anti-oxidative stress properties, and little is known about its role in male reproduction. This study was aimed at exploring the relationships among omentin-1/ITLN1, semen parameters and F Patients and Methods: Semen samples of infertile patients with varicocele (n = 27), genitourinary infections (n = 17), idiopathic infertility (n = 15) and fertile men (n = 21) were analyzed following WHO guidelines, and seminal plasma were used to determine omentin-1/ITLN1 by ELISA and F Results: Considering all participants, F Conclusion: Semen omentin-1/ITLN1 originates from seminal vesicles, its levels increase in inflammatory conditions and are negatively correlated with sperm parameters. For this reason, a sort of protective role of omentin-1/ITLN1 can be postulated, as this adipokine shows anti-inflammatory properties also in many other biological systems.

Indexed as

adipocytokinesepididymisF2-isoprostaneshuman spermimmunocytochemistryseminal vesicles

Identifiers

PMID35370415
PMCPMC8967990
OpenAlexW4221110028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.