Evidence map›Paper›PMID 35370411›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2022

Relationship Analysis of Inorganic Arsenic Exposure and Metabolic Syndrome Based on Propensity Score Matching in Xinjiang, China.

Yanwu Nie, Chenchen Wang, Lei Yang, Zhen Yang, Yahong Sun, Maozai Tian, Yuhua Ma, Yuxia Zhang, Yimu Yuan, Liping Zhang

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yanwu Nie *State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, School of Public Health, Xinjiang Medical University, Urumqi, 830017, People's Republic of China.
Chenchen Wang *Center for Disease Control and prevention of Xinjiang Uygur Autonomous Region, Urumqi, 830017, People's Republic of China.
Lei YangSchool of Nursing, Xinjiang Medical University, Urumqi, 830017, People's Republic of China.
Zhen YangSchool of Public Health, Xinjiang Medical University, Urumqi, 830017, People's Republic of China.
Yahong SunSchool of Public Health, Xinjiang Medical University, Urumqi, 830017, People's Republic of China.
Maozai TianCenter for Applied Statistics, School of Statistics, Renmin University of China, Beijing, 100872, People's Republic of China.ORCID 0000-0002-0515-4477
Yuhua MaDepartment of Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, People's Republic of China.
Yuxia ZhangDepartment of Clinical Nutrition, Urumqi Maternal and Child Health Institute, Urumqi, 830001, People's Republic of China.
Yimu YuanDepartment of General Practice Medicine, Xinjiang Corps Hospital, Urumqi, People's Republic of China.
Liping ZhangCollege of Medical Engineering and Technology, Xinjiang Medical University, Urumqi, 830017, People's Republic of China.
Xinjiang Medical University · CNMaternal and Child Health Hospital of Xinjiang Uygur Autonomous Region · CNShanghai East Hospital · CNXinjiang Uygur Autonomous Region Disease Prevention and Control Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The role of inorganic arsenic (iAs) in the risk of metabolic syndrome (MetS) remains unclear. This investigation focused on the effect of iAs exposure on MetS and whether the results are consistent in different subgroups. Patients and Methods: The present study was conducted on 629 men and 616 women aged 35-70 years and living in Xinjiang Uygur Autonomous Region, China. The 1:1 propensity score matching (PSM) was adopted to regulate the confounding factors, and the multivariate logistic regression was performed to assess the relationship between urinary iAs and MetS. Results: The median content of urinary iAs was examined as 2.20 μg/dL (interquartile range: 1.30-3.20 μg/dL), and the MetS prevalence reached 23.69% (295 cases/950 participants). After the confounding factors were adjusted, the ORs (95% CIs) for MetS from the minimal to the maximum urinary iAs quartiles reached 1.171 (0.736,1.863), 1.568 (1.008, 2.440) and 2.011 (1.296, 3.120), respectively (referencing 1.00) (P for trend=0.001). After the PSM, the urinary iAs content still plays a potential prediction role in MetS (P for trend=0.011). In addition, as revealed from the subgroup analysis, the urinary iAs content was a predictor of MetS in the female patients, whereas it did not serve as a significant predictor of MetS in the male patients (P for interaction<0.05). Conclusion: The increased urinary iAs content was associated with the increased prevalence of MetS in Chinese population. More attention should be paid to female urinary iAs content to avoid the high prevalence of MetS.

Indexed as

metabolic syndromepropensity score matchingsubgroup analysisurinary inorganic arsenic

Identifiers

PMID35370411
PMCPMC8965335
OpenAlexW4220769273

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.