Evidence map›Paper›PMID 35370394›Full record

ReviewCurrent treatment options in neurology2022

Treatment Approaches for Functional Neurological Disorders in Children.

Areti Vassilopoulos, Shekeeb Mohammad, Leon Dure, Kasia Kozlowska, Aaron D Fobian

Abstract readReview
In one paragraph

Review in Current treatment options in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Treating CRPS and FNSD in an Adolescent: A Case Study.Journal of clinical psychology in medical settings · 2026
    Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Areti VassilopoulosYale Child Study Center at Yale School of Medicine, New Haven, CT USA.ORCID 0000-0003-4051-4260
Shekeeb MohammadTY Nelson Department of Neurology and Neurosurgery, The Children's Hospital at Westmead, Sydney, NSW 2145 Australia.ORCID 0000-0003-1219-4781
Leon DureDepartments of Pediatrics and Neurology, University of Alabama at Birmingham, Birmingham, AL USA.ORCID 0000-0002-7883-4457
Kasia Kozlowska *Department of Psychological Medicine, The Children's Hospital at Westmead, Sydney, NSW 2145 Australia.ORCID 0000-0002-9578-0753
Aaron D Fobian *Department of Psychiatry, University of Alabama at Birmingham, Birmingham, AL USA.ORCID 0000-0001-9974-8534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose of Review: Functional neurological disorder (FND) is a multi-network brain disorder that encompasses a broad range of neurological symptoms. FND is common in pediatric practice. It places substantial strains on children, families, and health care systems. Treatment begins at assessment, which requires the following: the Recent Findings: Over the past decade, three treatment approaches-Retraining and Control Therapy (ReACT), other cognitive-behavioral therapies, and multidisciplinary rehabilitation-have been evaluated in the USA, Canada, and Australia. Of children treated in such programs, 63 - 95% showed full resolution of FND symptoms. The common thread across the programs is their biopsychosocial approach-consideration of biological, psychological, relational, and school-related factors that contribute to the child's clinical presentation. Summary: Current research strongly supports a biopsychosocial approach to pediatric FND and provides a foundation for a stepped approach to treatment. Stepped care is initially tailored to the needs of the individual child (and family) based on the pattern and severity of FND presentation. The level of care and type of intervention may then be adjusted to consider the child's response, over time, to treatment or treatment combinations. Future research is needed to confirm effective treatment targets, to inform the development of stepped care, and to improve methodologies that can assess the efficacy of stepped-care interventions.

Indexed as

Clinical ethicsFunctional neurological disorder (FND)Functional seizuresPediatricPsychogenic non-epileptic seizuresTreatment

Identifiers

PMID35370394
PMCPMC8958484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.