ArticleInternal medicine (Tokyo, Japan)2022
Oxaliplatin-related Portal Hypertension Complicated with Esophageal Varices and Refractory Massive Ascites.
Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Upper Gastrointestinal Bleeding Due to Ruptured Gastric Varices: A Diagnostic Challenge.Cureus · 2026Article
- Comparison of pharmacovigilance and mechanism analysis of the vascular toxicity caused by platin-based chemotherapy: integration of FAERS analysis, network pharmacology, and endothelial validation.Therapeutic advances in drug safety · 2026Article
- The "appearing" and "disappearing" ascites in the treatment of colorectal cancer: a case report.Frontiers in oncology · 2024Article
- Cataclysmic Gastrointestinal Hemorrhage: Dreaded Complication of Metastatic Breast Cancer.Cureus · 2022Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxaliplatin, widely used as a chemotherapy drug for colorectal cancer, is known to cause various adverse reactions. In particular, special attention for the development of portal hypertension associated with porto-sinusoidal vascular disease is necessary, as it is a serious adverse life-threating reaction, although rare. We herein report a case of oxaliplatin-related portal hypertension that developed several years after oxaliplatin administration and led to esophageal varices and refractory massive ascites. Clinical physicians should be aware of the possibility of oxaliplatin-induced portal hypertension and its possible development over a long period after discontinuation of the drug.
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