Evidence map›Paper›PMID 35369822›Full record

ArticleJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2022

Development of a droplet digital PCR assay for quantification of the proviral load of bovine leukemia virus.

María L De Brun, Bruno Cosme, Marcos Petersen, Irene Alvarez, Aurea Folgueras-Flatschart, Roberto Flatschart, Carlos Javier Panei, Rodrigo Puentes

Abstract read
In one paragraph

Article in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Droplet digital PCR (ddPCR) for enhanced detection and quantification of bovine viral diarrhea virus (BVDV): A promising tool for disease control.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

María L De BrunInstituto de Patobiología, Unidad de Microbiología, Facultad de Veterinaria-Universidad de la República, Montevideo, Uruguay.ORCID https://orcid.org/0000-0002-3331-9566
Bruno CosmeInstituto Nacional de Metrología, Calidad y Tecnología (Inmetro), Rio de Janeiro, Brazil.
Marcos PetersenInstituto Nacional de Tecnología Agropecuaria (INTA), Instituto de Virología e Innovaciones Tecnológicas (IVIT), Buenos Aires, Argentina.
Irene AlvarezInstituto Nacional de Tecnología Agropecuaria (INTA), Instituto de Virología e Innovaciones Tecnológicas (IVIT), Buenos Aires, Argentina.ORCID https://orcid.org/0000-0001-5194-670X
Aurea Folgueras-FlatschartInstituto Nacional de Metrología, Calidad y Tecnología (Inmetro), Rio de Janeiro, Brazil.
Roberto FlatschartInstituto Nacional de Metrología, Calidad y Tecnología (Inmetro), Rio de Janeiro, Brazil.
Carlos Javier PaneiLaboratorio de Virología, Facultad de Ciencias Veterinarias, Universidad Nacional de la Plata (FCV-UNLP), La Plata, Argentina.
Rodrigo PuentesInstituto de Patobiología, Unidad de Microbiología, Facultad de Veterinaria-Universidad de la República, Montevideo, Uruguay.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Droplet digital PCR (ddPCR) is a highly sensitive tool developed for the detection and quantification of short-sequence variants-a tool that offers unparalleled precision enabling measurement of smaller-fold changes. We describe here the use of ddPCR for the detection of

Indexed as

Cattle DiseasesEnzootic Bovine LeukosisLeukemia Virus, BovineSheep DiseasesAnimalsCattleEnzyme-Linked Immunosorbent AssayProvirusesReal-Time Polymerase Chain ReactionSheepbovine leukemia virusdroplet digital PCRenzootic bovine leukosisproviral load

Identifiers

PMID35369822
PMCPMC9254064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.