Evidence map›Paper›PMID 35369701›Full record

ArticleCirculation. Cardiovascular interventions2022

Periprocedural Pericardial Effusion Complicating Transcatheter Left Atrial Appendage Occlusion: A Report From the NCDR LAAO Registry.

Matthew J Price, Miguel Valderrábano, Sarah Zimmerman, Daniel J Friedman, Saibal Kar, Jeptha P Curtis, Frederick A Masoudi, James V Freeman

Open access · greenAbstract read
In one paragraph

Article in Circulation. Cardiovascular interventions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Emergent Cardiac Surgery After Transcatheter Structural Heart Procedures: Narrative Review.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. "Steering" Toward Complete Left Atrial Appendage Closure.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Improving on the 5.JACC. Asia · 2022
    Article
  20. Transcatheter Left Atrial Appendage Closure Comes of Age.Journal of the Society for Cardiovascular Angiography & Interventions
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Matthew J PriceDivision of Cardiovascular Diseases, Scripps Clinic, La Jolla, CA (M.J.P.).ORCID 0000-0002-7892-2430
Miguel ValderrábanoDivision of Cardiac Electrophysiology, Houston Methodist Hospital, TX (M.V.).ORCID 0000-0002-8401-1684
Sarah ZimmermanCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, CT (S.Z., J.P.C., J.V.F.).ORCID 0000-0003-0219-8498
Daniel J FriedmanElectrophysiology Section, Duke University Hospital, Durham, NC (D.J.F.).ORCID 0000-0001-5791-1954
Saibal KarLos Robles Regional Medical Center, Thousand Oaks, CA (S.K.).ORCID 0000-0003-1547-4869
Jeptha P CurtisCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, CT (S.Z., J.P.C., J.V.F.).ORCID 0000-0002-6872-0501
Frederick A MasoudiAscension Health, St Louis, MO (F.A.M.).
James V FreemanCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, CT (S.Z., J.P.C., J.V.F.).ORCID 0000-0002-4614-6879
Yale New Haven Hospital · USAscension · USDuke University Hospital · USHouston Methodist · USLos Robles Hospital & Medical Center · USScripps Clinic · US

Funding

Vein of Marshall Ethanol Infusion for Persistent Atrial FibrillationR01HL115003 · NHLBI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI VALDERRABANO, MIGUEL · 2013 to 2017
$3.6M
Safety and Effectiveness of Left Atrial Appendage Closure in Atrial Fibrillation (SAFELY-AF)R01HL142765 · NHLBI · YALE UNIVERSITY · PI FREEMAN, JAMES · 2019 to 2022
$2.9M
Safety and Effectiveness of Left Atrial Appendage Closure in Atrial Fibrillation (SAFELY-AF)R56HL142765 · NHLBI · YALE UNIVERSITY · PI FREEMAN, JAMES · 2018 to 2018
$657k
NHLBI NIH HHS R01 HL115003NHLBI NIH HHS R01 HL142765NHLBI NIH HHS R56 HL142765
6 · The paper itself

Abstract

backgroundPericardial effusion (PE) is a potential complication of transcatheter left atrial appendage occlusion. The objective of this study was to investigate the incidence, associated characteristics, and outcomes of PE following left atrial appendage occlusion.

methodsPatients in the NCDR LAAO Registry who underwent a Watchman procedure between January 1, 2016 and December 31, 2019 were included. The primary outcome was in-hospital PE requiring intervention (percutaneous drainage or surgery). Odds ratios (ORs) were calculated for adverse event rates associated with PE.

resultsThe study population consisted of 65 355 patients. The mean patient age was 76.2±8.1 years, and the mean CHA

conclusionsIn-hospital PE during transcatheter left atrial appendage occlusion is infrequent but associated with a substantially higher risk of adverse events, including in-hospital and early postdischarge mortality. Strategies to minimize PE are critical to improve the risk-benefit ratio for this therapy.

Indexed as

Atrial AppendageAtrial FibrillationEmbolismPericardial EffusionStrokeAftercareAgedAged, 80 and overFemaleHumansPatient DischargeRegistriesTreatment Outcomeanticoagulantsatrial fibrillationpericardial effusion

Identifiers

PMID35369701
PMCPMC9132377
OpenAlexW4225256058

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.