Evidence map›Paper›PMID 35369611›Full record

ReviewPostepy dermatologii i alergologii2022

Benzophenone-3, a chemical UV-filter in cosmetics: is it really safe for children and pregnant women?

Weronika Wnuk, Klaudia Michalska, Anna Krupa, Krystyna Pawlak

Open access · goldAbstract readReview
In one paragraph

Review in Postepy dermatologii i alergologii, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 60 citations in OpenAlex.

  1. The MAK collection for occupational health and safety · 2026
    Review
  2. Article
  3. Review
  4. Adult withdrawal of long-term Benzophenone-3 treatment induces regression of mammary ductal branching in a diet-dependent manner.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Sunscreens: A narrative review.Skin health and disease · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Sunscreen compound benzophenone-3 and its relationship with white blood cell counts.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Toxics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Weronika WnukDepartment of Monitored Pharmacotherapy, Medical University of Bialystok, Bialystok, Poland.
Klaudia MichalskaDepartment of Monitored Pharmacotherapy, Medical University of Bialystok, Bialystok, Poland.
Anna KrupaDepartment of Monitored Pharmacotherapy, Medical University of Bialystok, Bialystok, Poland.
Krystyna PawlakDepartment of Monitored Pharmacotherapy, Medical University of Bialystok, Bialystok, Poland.
Medical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children and adolescents are particularly vulnerable to skin damage caused by ultraviolet radiation and require intensified photoprotection. Benzophenone-3 (BP-3) belongs to the organic sunscreens, which are widely used in personal care and cosmetic products. However, the impact of BP-3 on human health requires a careful assessment. This review focuses on potentially harmful effect of this compound in relation to the developing organism. Studies show that BP-3, after topical application, can penetrate into bloodstream, blood-brain barrier and blood-placental barrier and may induce the reproductive toxicity and abnormal development of the foetus, endocrine system disruption and neurotoxicity in experimental animal models. So far, human studies have been scarce and controversial, therefore the cosmetics containing BP-3 should be carefully used by the pregnant women, children and adolescents.

Indexed as

benzophenone-3cosmeticsdevelopmental toxicityendocrine disruptionneurotoxicity

Identifiers

PMID35369611
PMCPMC8953895
OpenAlexW4214718854

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.