Evidence map›Paper›PMID 35369516›Full record

ArticleFrontiers in microbiology2022

Appraisal of Cinnamaldehyde Analogs as Dual-Acting Antibiofilm and Anthelmintic Agents.

Sagar Kiran Khadke, Jin-Hyung Lee, Yong-Guy Kim, Vinit Raj, Jintae Lee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Antibiofilm Activities of Cinnamaldehyde Analogs against UropathogenicInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sagar Kiran KhadkeSchool of Chemical Engineering, Yeungnam University, Gyeongsan, South Korea.
Jin-Hyung LeeSchool of Chemical Engineering, Yeungnam University, Gyeongsan, South Korea.
Yong-Guy KimSchool of Chemical Engineering, Yeungnam University, Gyeongsan, South Korea.
Vinit RajSchool of Chemical Engineering, Yeungnam University, Gyeongsan, South Korea.
Jintae LeeSchool of Chemical Engineering, Yeungnam University, Gyeongsan, South Korea.
Yeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cinnamaldehyde has a broad range of biological activities, which include antibiofilm and anthelmintic activities. The ever-growing problem of drug resistance and limited treatment options have created an urgent demand for natural molecules with antibiofilm and anthelmintic properties. Hence, we hypothesized that molecules with a scaffold structurally similar to that of cinnamaldehyde might act as dual inhibitors against fungal biofilms and helminths. In this regard, eleven cinnamaldehyde analogs were tested to determine their effects on fungal

Indexed as

anthelminticantibiofilmCandida albicansprotein interactiontrans-4-methyl cinnamaldehydeα-methyl cinnamaldehyde

Identifiers

PMID35369516
PMCPMC8966877
OpenAlexW4220774411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.